The combination of ferroptosis and innovative tumor therapy methods offers another
promising answer to the problem of tumors. In order to generate effective ferroptosis in tumor …

Background: Ferroptosis is a form of iron-dependent programmed cell death that differs from
apoptosis with regards to both mechanism and cell morphology. Therefore, ferroptotic-based …

Although ferroptosis plays a potential role in sensitizing tumor radiotherapy, its
radiosensitization efficacy is still limited by insufficient endogenous H 2 O 2 and excess …

The upregulation of dihydroorotate dehydrogenase (DHODH) redox systems inside tumor
cells provides a powerful shelter against lipid peroxidation (LPO), impeding ferroptosis …

High cobalt (Co) levels in tumors are associated with good clinical prognosis. An anticancer
regimen that increases intratumoral Co through targeted nanomaterial delivery is proposed …

Ferroptosis offers a novel method for overcoming therapeutic resistance of cancers to
conventional cancer treatment regimens. Its effective use as a cancer therapy requires a …

Radiotherapy (RT) is one of the important clinical treatments for local control of triple-
negative breast cancer (TNBC), but radioresistance still exists. Ferroptosis has been …

A potential reason for the failure of tumor therapies is treatment resistance. Resistance to
chemotherapy, radiotherapy, and immunotherapy continues to be a major obstacle in clinic …

Ferroptosis is an iron-dependent form of cell death that is also a promising tumor therapeutic
modality, however, maintaining redox and iron homeostasis in tumor cells limits the …

Ferroptosis is a new form of regulated cell death with significant therapeutic prospect, but its
application against drug‐resistant tumor cells is challenging due to their ability to effuse …