Smart active-targeting of lipid-polymer hybrid nanoparticles for therapeutic applications: Recent advances and challenges

L Khalili, G Dehghan, N Sheibani, A Khataee - International Journal of …, 2022 - Elsevier
The advances in producing multifunctional lipid-polymer hybrid nanoparticles (LPHNs) by
combining the biomimetic behavior of liposomes and architectural advantages of polymers …

Lipid–polymer hybrid nanosystems: a rational fusion for advanced therapeutic delivery

S Jain, M Kumar, P Kumar, J Verma… - Journal of Functional …, 2023 - mdpi.com
Lipid nanoparticles (LNPs) are spherical vesicles composed of ionizable lipids that are
neutral at physiological pH. Despite their benefits, unmodified LNP drug delivery systems …

Lipid–polymer hybrid nanoparticle-mediated therapeutics delivery: advances and challenges

RJC Bose, R Ravikumar, V Karuppagounder… - Drug discovery today, 2017 - Elsevier
Highlights•This review gives an update of LPHNPs manufacturing process and therapeutics
delivery•LPHNPs can be used for improving the therapeutic efficacy of drugs, genes and …

[HTML][HTML] Polymeric lipid hybrid nanoparticles (plns) as emerging drug delivery platform—A comprehensive review of their properties, preparation methods, and …

D Sivadasan, MH Sultan, O Madkhali, Y Almoshari… - Pharmaceutics, 2021 - mdpi.com
Polymeric lipid hybrid nanoparticles (PLNs) are core–shell nanoparticles made up of a
polymeric kernel and lipid/lipid–PEG shells that have the physical stability and …

Lipid–polymer hybrid nanoparticles as a next-generation drug delivery platform: state of the art, emerging technologies, and perspectives

A Mukherjee, AK Waters, P Kalyan… - International journal …, 2019 - Taylor & Francis
Lipid–polymer hybrid nanoparticles (LPHNPs) are next-generation core–shell
nanostructures, conceptually derived from both liposome and polymeric nanoparticles …

Core–shell-type lipid–polymer hybrid nanoparticles as a drug delivery platform

B Mandal, H Bhattacharjee, N Mittal, H Sah… - … , Biology and Medicine, 2013 - Elsevier
The focus of nanoparticle design over the years has evolved toward more complex
nanoscopic core–shell architecture using a single delivery system to combine multiple …

[HTML][HTML] Lipid polymer hybrid nanocarriers: Insights into synthesis aspects, characterization, release mechanisms, surface functionalization and potential implications

S Shah, P Famta, RS Raghuvanshi, SB Singh… - Colloid and Interface …, 2022 - Elsevier
Lipid polymer hybrid nanoparticles (LPHN) are novel systems which are potentially
emerging in the era of nano-medicine. They are core-shell nanostructures which comprise of …

Lipid–polymer hybrid nanoparticles: synthesis, characterization and applications

LI Zhang, L Zhang - Nano life, 2010 - World Scientific
Nanotechnology has been extensively explored in the past decade to develop a myriad of
functional nanostructures to facilitate the delivery of therapeutic and imaging agents for …

Lipid–polymer hybrid nanoparticles as a new generation therapeutic delivery platform: a review

K Hadinoto, A Sundaresan, WS Cheow - European journal of …, 2013 - Elsevier
Lipid–polymer hybrid nanoparticles (LPNs) are core–shell nanoparticle structures
comprising polymer cores and lipid/lipid–PEG shells, which exhibit complementary …

An update on strategies for optimizing polymer-lipid hybrid nanoparticle-mediated drug delivery: exploiting transformability and bioactivity of PLN and harnessing …

T Ahmed, FCF Liu, XY Wu - Expert Opinion on Drug Delivery, 2024 - Taylor & Francis
Introduction Polymer-lipid hybrid nanoparticle (PLN) is an emerging nanoplatform with
distinct properties and functionalities from other nanocarrier systems. PLN can be optimized …