Objective To investigate the contribution of K+ channels on peripheral antinociception
induced by ketamine. Study design Prospective experimental study. Animals 110 male …

Xylazine is an α 2-adrenergic agonist extensively used in veterinary medicine and animal
experimentation for producing antinociception, sedation, and muscle relaxation. The nitric …

Using the rat paw pressure test, in which sensitivity is increased by intraplantar injection of
prostaglandin E2 (PGE2), we conducted a study using several K+ channel blockers. The …

Background Central sensitization is a potential severe consequence of invasive surgical
procedures. It results in postoperative and potentially chronic pain enhancement. It results in …

We evaluated the effect of several K+ channel blockers on the peripheral antinociception
induced by dipyrone using the rat paw pressure test, in which sensitivity is increased by …

The effect of several K+ channel blockers such as glibenclamide, tolbutamide,
charybdotoxin (ChTX), apamin, tetraethylammonium (TEA), 4‐aminopyridine (4‐AP) and …

In order to investigate to the contribution of K+ channels on the peripheral antinociception
induced by diclofenac, we evaluated the effect of several K+ channel blockers, using the rat …

This study quantitatively investigated the analgesic action of a low-dose constant-rate-
infusion (CRI) of racemic ketamine (as a 0.5 mgkg− 1 bolus and at a dose rate of 10μgkg …

We examined the effect of several K+ channel blockers such as glibenclamide, tolbutamide,
charybdotoxin (ChTX), apamin, tetraethylammonium chloride (TEA), 4-aminopyridine (4-AP) …

The involvement of K+ channels in the antinociceptive action of diclofenac was assessed in
the formalin test. Local administration of diclofenac produced a dose-dependent …