APOE genotype moderates the relationship between LRP1 polymorphism and cognition across the Alzheimer's disease spectrum via disturbing default mode network
F Zang, Y Zhu, Q Zhang, C Tan, Q Wang… - CNS Neuroscience …, 2021 - Wiley Online Library
Aims This study aims to investigate the mechanisms by which apolipoprotein E (APOE)
genotype modulates the relationship between low‐density lipoprotein receptor‐related …
genotype modulates the relationship between low‐density lipoprotein receptor‐related …
Default mode network connectivity moderates the relationship between the APOE genotype and cognition and individualizes identification across the Alzheimer's …
Although previous studies have investigated the effects of the apolipoprotein E (APOE) 4
genotype on the default mode network (DMN) in the Alzheimer's disease (AD) spectrum, it is …
genotype on the default mode network (DMN) in the Alzheimer's disease (AD) spectrum, it is …
Differential effects of APOE genotypes on the anterior and posterior subnetworks of default mode network in amnestic mild cognitive impairment
B Yuan, C Xie, H Shu, W Liao, Z Wang… - Journal of …, 2016 - content.iospress.com
Background: The apolipoprotein E (APOE) ɛ4 carriers are at increased risk of developing
Alzheimer's disease (AD) while the ɛ2 carriers appear to be protected against the disease …
Alzheimer's disease (AD) while the ɛ2 carriers appear to be protected against the disease …
The tt allele of rs405509 synergizes with apoe 4 in the impairment of cognition and its underlying default mode network in non-demented elderly
Background: Evidence demonstrates that the T allele of the single-nucleotide polymorphism
rs405509 as the apolipoprotein E (APOE) promoter is a risk factor for Alzheimer's disease …
rs405509 as the apolipoprotein E (APOE) promoter is a risk factor for Alzheimer's disease …
APOE effects on default mode network in Chinese cognitive normal elderly: relationship with clinical cognitive performance
H Song, H Long, X Zuo, C Yu, B Liu, Z Wang, Q Wang… - PLoS …, 2015 - journals.plos.org
Background Functional connectivity in default mode network (DMN) may be changed in
Alzheimer's disease (AD) patients and related risk populations, such as amnestic mild …
Alzheimer's disease (AD) patients and related risk populations, such as amnestic mild …
Association of the LRP1 gene and cognitive performance with amnestic mild cognitive impairment in elderly Chinese
YM Shi, H Zhou, ZJ Zhang, H Yu, F Bai… - International …, 2009 - cambridge.org
Background: The genetic region coding for low-density lipoprotein receptor-related protein1
(LRP1) is considered an intriguing susceptibility locus for Alzheimer's disease (AD) …
(LRP1) is considered an intriguing susceptibility locus for Alzheimer's disease (AD) …
Recognition memory is associated with altered resting‐state functional connectivity in people at genetic risk for Alzheimer's disease
S Matura, D Prvulovic, M Butz… - European Journal of …, 2014 - Wiley Online Library
The apolipoprotein E ε4 (ApoE ε4) allele not only represents the strongest single genetic risk
factor for sporadic Alzheimer's disease, but also imposes independent effects on brain …
factor for sporadic Alzheimer's disease, but also imposes independent effects on brain …
Association between LRP1 C766T polymorphism and Alzheimer's disease susceptibility: a meta-analysis
Y Wang, S Liu, J Wang, J Zhang, Y Hua, H Li, H Tan… - Scientific reports, 2017 - nature.com
Low density lipoprotein receptor-related protein 1 (LRP1) C766T polymorphism (rs1799986)
has been extensively investigated for Alzheimer's disease (AD) susceptibility. However …
has been extensively investigated for Alzheimer's disease (AD) susceptibility. However …
[HTML][HTML] Functional co-activation of the default mode network in APOE ε4-carriers: A replication study
Structural and functional alterations of the brain in persons genetically at-risk for Alzheimer's
disease (AD) are crucial in unravelling AD development. Filippini et al. found that the default …
disease (AD) are crucial in unravelling AD development. Filippini et al. found that the default …
The relationship between APOE genotype, CSF Tau and cognition across the Alzheimer's disease spectrum, moderation and mediation role of insula network …
Y Zhu, Y Wu, X Lv, J Wu, C Shen… - CNS Neuroscience …, 2024 - Wiley Online Library
Aims To investigate whether insula network connectivity modulates the relationship between
apolipoprotein E (APOE) ε4 genotype, cerebrospinal fluid (CSF) biomarkers (Aβ, Tau, and …
apolipoprotein E (APOE) ε4 genotype, cerebrospinal fluid (CSF) biomarkers (Aβ, Tau, and …