The contribution of immune and glial cell types in experimental autoimmune encephalomyelitis and multiple sclerosis

SS Duffy, JG Lees… - Multiple sclerosis …, 2014 - Wiley Online Library
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
characterised by widespread areas of focal demyelination. Its aetiology and pathogenesis …

Pathologic and protective roles for microglial subsets and bone marrow-and blood-derived myeloid cells in central nervous system inflammation

A Wlodarczyk, O Cédile, KN Jensen, A Jasson… - Frontiers in …, 2015 - frontiersin.org
Inflammation is a series of processes designed for eventual clearance of pathogens and
repair of damaged tissue. In the context of autoimmune recognition, inflammatory processes …

Do not judge a cell by its cover—diversity of CNS resident, adjoining and infiltrating myeloid cells in inflammation

SM Brendecke, M Prinz - Seminars in immunopathology, 2015 - Springer
Specialized populations of tissue-resident myeloid cells inhabit every organ of the body.
While many of these populations appear similar morphologically and phenotypically, they …

Multiple sclerosis and T lymphocytes: an entangled story

L Legroux, N Arbour - Journal of Neuroimmune Pharmacology, 2015 - Springer
Multiple sclerosis (MS) is the prototypic inflammatory disease of the central nervous system
(CNS) characterized by multifocal areas of demyelination, axonal damage, activation of glial …

Macrophages: a double-edged sword in experimental autoimmune encephalomyelitis

Z Jiang, JX Jiang, GX Zhang - Immunology letters, 2014 - Elsevier
Multiple sclerosis (MS) is a debilitating neurological disorder of the central nervous system
(CNS), characterized by activation and infiltration of leukocytes and dendritic cells into the …

Role of peripheral immune cells in multiple sclerosis and experimental autoimmune encephalomyelitis

S Dhaiban, M Al-Ani, NM Elemam, MH Al-Aawad… - Sci, 2021 - mdpi.com
Multiple sclerosis (MS) is a chronic autoimmune disease that affects the myelination of the
neurons present in the central nervous system (CNS). The exact etiology of MS development …

Communication between pathogenic T cells and myeloid cells in neuroinflammatory disease

L Codarri, M Greter, B Becher - Trends in immunology, 2013 - cell.com
Clinical and experimental data suggest that T helper (TH) cells are involved in the
pathogenicity of experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis …

Role of the innate immune system in the pathogenesis of multiple sclerosis

R Gandhi, A Laroni, HL Weiner - Journal of neuroimmunology, 2010 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease with heterogeneous
clinical presentations and course. MS is considered to be a T cell mediated disease but in …

New insights into cell responses involved in experimental autoimmune encephalomyelitis and multiple sclerosis

M El Behi, S Dubucquoi, D Lefranc, H Zéphir… - Immunology letters, 2005 - Elsevier
Animal models of autoimmune diseases such as experimental autoimmune
encephalomyelitis (EAE) are inflammatory demyelinating diseases which comprise a …

Models of autoimmune demyelination in the central nervous system: on the way to translational medicine

RA Linker, DH Lee - Experimental & translational stroke medicine, 2009 - Springer
Multiple sclerosis (MS) is the most common neurologic disease of young adults. In the recent
years, our understanding on disease pathomechanisms has considerably improved and …