[HTML][HTML] Molecular mechanisms of neurogenic lower urinary tract dysfunction after spinal cord injury

N Shimizu, T Saito, N Wada, M Hashimoto… - International journal of …, 2023 - mdpi.com
This article provides a synopsis of current progress made in fundamental studies of lower
urinary tract dysfunction (LUTD) after spinal cord injury (SCI) above the sacral level. Animal …

[HTML][HTML] Current knowledge and novel frontiers in lower urinary tract dysfunction after spinal cord injury: Basic research perspectives

N Wada, S Karnup, K Kadekawa, N Shimizu… - Urological …, 2022 - journals.lww.com
This review article aims to summarize the recent advancement in basic research on lower
urinary tract dysfunction (LUTD) following spinal cord injury (SCI) above the sacral level. We …

[HTML][HTML] Molecular characterization of non-neurogenic and neurogenic lower urinary tract dysfunction (LUTD) in SCI-induced and partial bladder outlet obstruction …

M von Siebenthal, A Akshay, M Besic… - International journal of …, 2023 - mdpi.com
We examined bladder function following spinal cord injury (SCI) by repeated urodynamic
investigation (UDI), including external urethral sphincter (EUS) electromyography (EMG) in …

Bladder afferent pathway and spinal cord injury: possible mechanisms inducing hyperreflexia of the urinary bladder

N Yoshimura - Progress in neurobiology, 1999 - Elsevier
Lower urinary tract dysfunction is a common problem in patients with spinal cord injury (SCI).
Since the coordination of the urinary bladder and urethra is controlled by the complex …

Time-dependent progression of neurogenic lower urinary tract dysfunction after spinal cord injury in the mouse model

T Saito, D Gotoh, N Wada, P Tyagi… - American Journal …, 2021 - journals.physiology.org
This study evaluated the time-course changes in bladder and external urinary sphincter
(EUS) activity and the expression of mechanosensitive channels in lumbosacral dorsal root …

[HTML][HTML] Assessing neurogenic lower urinary tract dysfunction after spinal cord injury: Animal models in preclinical neuro-urology research

AW Doelman, F Streijger, SJA Majerus, MS Damaser… - Biomedicines, 2023 - mdpi.com
Neurogenic bladder dysfunction is a condition that affects both bladder storage and voiding
function and remains one of the leading causes of morbidity after spinal cord injury (SCI) …

Influence of spinal cord injury on the morphology of bladder afferent and efferent neurons

MN Kruse, LA Bray, WC De Groat - Journal of the autonomic nervous …, 1995 - Elsevier
Severe micturition dysfunction can occur following spinal cord injury (SCI) due to abnormal
contractions of the urethral sphincter during bladder contractions (bladder/sphincter …

Coordination of the bladder detrusor and the external urethral sphincter in a rat model of spinal cord injury: effect of injury severity

V Pikov, JR Wrathall - Journal of Neuroscience, 2001 - Soc Neuroscience
Recovery of urinary tract function after spinal cord injury (SCI) is important in its own right
and may also serve as a model for studying mechanisms of functional recovery after injury in …

Plasticity in the injured spinal cord: can we use it to advantage to reestablish effective bladder voiding and continence?

NDT Zinck, JW Downie - Progress in Brain Research, 2006 - Elsevier
Micturition is coordinated at the level of the spinal cord and the brainstem. Spinal cord injury
therefore directly interrupts spinal neuronal pathways to the brainstem and results in bladder …

Pharmacologic and potential biologic interventions to restore bladder function after spinal cord injury

N Yoshimura, CP Smith, MB Chancellor… - Current opinion in …, 2000 - journals.lww.com
Spinal cord injury disrupts voluntary control of voiding and the normal reflex pathways that
coordinate bladder and urethral sphincter function. The present review addresses studies in …