Roles of NF-κB signaling in the regulation of miRNAs impacting on inflammation in cancer

GS Markopoulos, E Roupakia, M Tokamani, G Alabasi… - Biomedicines, 2018 - mdpi.com
The NF-κB family of transcription factors regulate the expression of genes encoding proteins
and microRNAs (miRNA, miR) precursors that may either positively or negatively regulate a …

MicroRNA roles in the nuclear factor kappa B signaling pathway in cancer

J Wu, J Ding, J Yang, X Guo, Y Zheng - Frontiers in Immunology, 2018 - frontiersin.org
Nuclear factor kappa B (NF-κB) is a pluripotent and crucial dimer transcription factor that
orchestrates various physiological and pathological processes, especially cell proliferation …

MicroRNAs in NF-κB signaling

X Ma, LE Becker Buscaglia… - Journal of molecular cell …, 2011 - academic.oup.com
Nuclear factor κB (NF-κB) is a transcriptional factor that regulates a battery of genes that are
critical to innate and adaptive immunity, cell proliferation, inflammation, and tumor …

An NF-κB-microRNA regulatory network tunes macrophage inflammatory responses

M Mann, A Mehta, JL Zhao, K Lee, GK Marinov… - Nature …, 2017 - nature.com
The innate inflammatory response must be tightly regulated to ensure effective immune
protection. NF-κB is a key mediator of the inflammatory response, and its dysregulation has …

The complexity of NF-κB signaling in inflammation and cancer

B Hoesel, JA Schmid - Molecular cancer, 2013 - Springer
The NF-κB family of transcription factors has an essential role in inflammation and innate
immunity. Furthermore, NF-κB is increasingly recognized as a crucial player in many steps of …

[PDF][PDF] The functional analysis of MicroRNAs involved in NF-κB signaling

Y Yang, JK Wang - Eur Rev Med Pharmacol Sci, 2016 - europeanreview.org
Nuclear factor κB (NF-κB) is a transcriptional factor that regulates a large number of genes
that controls diverse biological functions, ranging from inflammation, cell proliferation and …

A functional genomics screen for microRNA regulators of NF-kappaB signaling

AO Olarerin-George, L Anton, YC Hwang, MA Elovitz… - BMC biology, 2013 - Springer
Abstract Background The nuclear factor-KappaB (NF-κB) pathway is conserved from fruit
flies to humans and is a key mediator of inflammatory signaling. Aberrant regulation of NF …

[HTML][HTML] Understanding the role of miRNA in regulating NF-κB in blood cancer

SA Rushworth, MY Murray, LN Barrera… - American journal of …, 2012 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by binding
to complementary sequences in mRNAs encoding downstream target genes. A large variety …

Regulation of Nuclear Factor-KappaB (NF-κB) signaling pathway by non-coding RNAs in cancer: Inhibiting or promoting carcinogenesis?

S Mirzaei, A Zarrabi, F Hashemi, A Zabolian, H Saleki… - Cancer Letters, 2021 - Elsevier
The nuclear factor-kappaB (NF-κB) signaling pathway is considered as a potential
therapeutic target in cancer therapy. It has been well established that transcription factor NF …

A modeled dynamic regulatory network of NF-κB and IL-6 mediated by miRNA

X Xue, W Xia, H Wenzhong - Biosystems, 2013 - Elsevier
The inflammatory response is a rapid and complex physiological reaction to infection, which
must be carefully modulated to remove pathogens and prevent the consequences of …