Nociceptin (NC), alias Orphanin FQ, has been recently identified as the endogenous ligand
of the opioid receptor‐like 1 receptor (OP4). This new NC/OP4 receptor system belongs to …

Nociceptin, also known as orphanin FQ, was recently identified as the naturally occurring
agonist of orphan opioid receptor-like ORL1 receptor (Meunier et al., 1995, Nature 377, 532; …

The neuropeptide nociceptin, also called orphanin FQ (N/OFQ), is the endogenous agonist
of the N/OFQ peptide receptor (NOP receptor). Both N/OFQ and the NOP receptor share a …

The cloning of a fourth member of the opioid receptor family has led to the discovery of a
new neuropeptide termed orphanin FQ or nociceptin (OFQ/N). Studies in CD-1 mice confirm …

Nociceptin (orphanin FQ) is a novel neuropeptide capable of inducing a variety of biological
actions via activation of a specific G‐protein coupled receptor. However, the lack of a …

Orphanin FQ, also known as nociceptin, is a heptadecapeptide with very high affinity for a
novel member of the cloned opioid receptor family which produces hyperalgesia in mice. In …

Nociceptin (NC), alias Orphanin FQ (OFQ) is a heptadecapeptide structurally related to
opioid peptides, especially Dynorphin A, which, however, does not interact with classic …

Nociceptin/orphanin FQ (N/OFQ) modulates several biological functions by activating a
specific G‐protein coupled receptor (NOP). Few molecules are available that selectively …

The isolation of an opioid receptor-related clone soon led to the isolation and
characterization of a new neuropeptide, termed orphanin FQ or nociceptin (OFQ/N). This …

Fifteen hexapeptides having high affinity for the opioid-like receptor ORL1 were identified
from a combinatorial library containing more than 52 million different hexapeptides. The five …