Coagulopathy and sepsis: Pathophysiology, clinical manifestations and treatment

M Giustozzi, H Ehrlinder, D Bongiovanni, JA Borovac… - Blood reviews, 2021 - Elsevier
Sepsis is a complex syndrome with a high incidence, increasing by 8.7% annually over the
last 20 years. Coagulopathy is a leading factor associated with mortality in patients with …

Sepsis-associated disseminated intravascular coagulation and its differential diagnoses

T Iba, E Watanabe, Y Umemura, T Wada… - Journal of intensive …, 2019 - Springer
Disseminated intravascular coagulation (DIC) is a common complication in sepsis. Since
DIC not only promotes organ dysfunction but also is a strong prognostic factor, its diagnosis …

Sepsis and thrombosis

M Levi, M Schultz, T van der Poll - Seminars in thrombosis and …, 2013 - thieme-connect.com
Activation of coagulation frequently occurs in severe infection and sepsis and may contribute
to the development of thrombosis. Coagulation abnormalities in sepsis range from a small …

Sepsis-induced coagulopathy and disseminated intravascular coagulation

T Iba, M Levi, JH Levy - Seminars in thrombosis and …, 2020 - thieme-connect.com
Disseminated intravascular coagulation (DIC) has been recognized as a deadly
complication in sepsis, and its early recognition followed by appropriate management of the …

Coagulopathy of sepsis

CE Dempfle - Thrombosis and haemostasis, 2004 - thieme-connect.com
Disseminated intravascular coagulation (DIC) is a common phenomenon in patients with
sepsis, but the clinical implications of this condition are not clear. Clinical trials with …

Advance in the management of sepsis-induced coagulopathy and disseminated intravascular coagulation

T Iba, JH Levy, A Raj, TE Warkentin - Journal of clinical medicine, 2019 - mdpi.com
Coagulopathy commonly occurs in sepsis as a critical host response to infection that can
progress to disseminated intravascular coagulation (DIC) with an increased mortality …

Pathogenesis and treatment of disseminated intravascular coagulation in the septic patient

M Levi - Journal of critical care, 2001 - Elsevier
The incidence of sepsis and complications stemming from septicemia has remained
constant in recent years despite improved levels of monitoring and care. Disseminated …

Coagulopathy of acute sepsis

N Semeraro, CT Ammollo, F Semeraro… - … in thrombosis and …, 2015 - thieme-connect.com
Coagulopathy is common in acute sepsis and may range from subclinical activation of blood
coagulation (hypercoagulability), which may contribute to venous thromboembolism, to …

Sepsis-induced coagulopathy: an update on pathophysiology, biomarkers, and current guidelines

AG Tsantes, S Parastatidou, EA Tsantes, E Bonova… - Life, 2023 - mdpi.com
Significant cross talk occurs between inflammation and coagulation. Thus, coagulopathy is
common in sepsis, potentially aggravating the prognosis. Initially, septic patients tend to …

The pathophysiology, diagnosis, and management of sepsis-associated disseminated intravascular coagulation

T Iba, J Helms, JM Connors, JH Levy - Journal of Intensive Care, 2023 - Springer
Abstract Background The International Society on Thrombosis and Haemostasis (ISTH)
released overt disseminated intravascular coagulation (DIC) diagnostic criteria in 2001 …