Background and Objectives To examine associations between indicators of estrogen
exposure from women's reproductive history and brain MRI biomarkers of Alzheimer disease …

Objective Women have> 50% greater lifetime risk of dementia than men but the role of
female-specific endocrine milieu is not well-understood. This study evaluates associations …

Background To date, there is no homogeneous evidence of whether earlier age at
menopause is associated with incident dementia. In addition, the underlying mechanism …

Objective: To determine the association between age at surgical menopause and both
cognitive decline and Alzheimer disease (AD) pathology in 2 longitudinal cohorts. Methods …

Objective To investigate sex differences in late-onset Alzheimer disease (AD) risks by
means of multimodality brain biomarkers (β-amyloid load via 11C-Pittsburgh compound B …

Background: Epidemiological studies suggest that proxies of higher lifetime estrogen
exposure are associated with better cognitive function in postmenopausal women, but this …

Abstract Purpose of Review The prevalence of Alzheimer's disease and related dementias is
greater in women compared to men. We provide a review of female sex-specific risk factors …

Objectives: To determine whether menopausal hormone therapy (HT) affects regional brain
volumes, including hippocampal and frontal regions. Methods: Brain MRI scans were …

Declining estrogen levels before, during, and after menopause can affect memory and risk
for Alzheimer's disease. Undesirable side effects of hormone variations emphasize a role for …

After advanced age, female sex is the major risk factor for late-onset Alzheimer's disease
(AD), the most common cause of dementia affecting over 24 million people worldwide. The …