Is euchromatin really open in the cell?
Genomic DNA is wrapped around a core histone octamer and forms a nucleosome. In
higher eukaryotic cells, strings of nucleosomes are irregularly folded as chromatin domains …
higher eukaryotic cells, strings of nucleosomes are irregularly folded as chromatin domains …
Physical nature of chromatin in the nucleus
K Maeshima, S Iida, S Tamura - Cold Spring Harbor …, 2021 - cshperspectives.cshlp.org
Genomic information is encoded on long strands of DNA, which are folded into chromatin
and stored in a tiny nucleus. Nuclear chromatin is a negatively charged polymer composed …
and stored in a tiny nucleus. Nuclear chromatin is a negatively charged polymer composed …
Methods for identifying higher-order chromatin structure
SA Sajan, RD Hawkins - Annual review of genomics and human …, 2012 - annualreviews.org
Eukaryotic genomic DNA is combined with histones, nonhistone proteins, and RNA to form
chromatin, which is extensively packaged hierarchically to fit inside a cell's nucleus. The …
chromatin, which is extensively packaged hierarchically to fit inside a cell's nucleus. The …
Chromatin structure: does the 30-nm fibre exist in vivo?
K Maeshima, S Hihara, M Eltsov - Current opinion in cell biology, 2010 - Elsevier
A long strand of DNA is wrapped around the core histone and forms a nucleosome.
Although the nucleosome has long been assumed to be folded into 30-nm chromatin fibres …
Although the nucleosome has long been assumed to be folded into 30-nm chromatin fibres …
New insights into nucleosome and chromatin structure: an ordered state or a disordered affair?
K Luger, ML Dechassa, DJ Tremethick - Nature reviews Molecular cell …, 2012 - nature.com
The compaction of genomic DNA into chromatin has profound implications for the regulation
of key processes such as transcription, replication and DNA repair. Nucleosomes, the …
of key processes such as transcription, replication and DNA repair. Nucleosomes, the …
Dynamic chromatin organization without the 30-nm fiber
K Maeshima, S Ide, M Babokhov - Current opinion in cell biology, 2019 - Elsevier
Chromatin in eukaryotic cells is a negatively charged polymer composed of DNA, histones,
and various associated proteins. Over the past ten years, our view of chromatin has shifted …
and various associated proteins. Over the past ten years, our view of chromatin has shifted …
Condensed chromatin behaves like a solid on the mesoscale in vitro and in living cells
The association of nuclear DNA with histones to form chromatin is essential for temporal and
spatial control of eukaryotic genomes. In this study, we examined the physical state of …
spatial control of eukaryotic genomes. In this study, we examined the physical state of …
Fluid-like chromatin: Toward understanding the real chromatin organization present in the cell
Eukaryotic chromatin is a negatively charged polymer consisting of genomic DNA, histones,
and various nonhistone proteins. Because of its highly charged character, the structure of …
and various nonhistone proteins. Because of its highly charged character, the structure of …
Chromatin higher-order structures and gene regulation
G Li, D Reinberg - Current opinion in genetics & development, 2011 - Elsevier
Genomic DNA in the eukaryotic nucleus is hierarchically packaged by histones into
chromatin to fit inside the nucleus. The dynamics of higher-order chromatin compaction play …
chromatin to fit inside the nucleus. The dynamics of higher-order chromatin compaction play …
Molecular complexes at euchromatin, heterochromatin and centromeric chromatin
O Morrison, J Thakur - International Journal of Molecular Sciences, 2021 - mdpi.com
Chromatin consists of a complex of DNA and histone proteins as its core components and
plays an important role in both packaging DNA and regulating DNA metabolic pathways …
plays an important role in both packaging DNA and regulating DNA metabolic pathways …