Neurological disorders have been increased in the last years, affecting over one billion
people globally. The lack of successful treatments is related to the low brain bioavailability of …

In the treatment of brain diseases, most potent drugs that have been developed exhibit poor
therapeutic outcomes resulting from the inability of a therapeutic amount of the drug to reach …

Neurological disorders have become severe and dreadful issues around the globe that are
rarely directly mediated because of the blood-brain barrier (BBB). Despite the various …

The discipline of nanoscience has made enormous strides in the recent two decades. The
researchers in the field of nanomedicine have been looking into using natural …

The major impediment to the delivery of therapeutics to the brain is the presence of the
blood-brain barrier (BBB). The BBB allows for the entrance of essential nutrients while …

It is well known that the central nervous system (CNS) has a limited regenerative capacity
and that many therapeutic molecules cannot cross the blood brain barrier (BBB). The use of …

Neurological diseases are known as global health problems with a growing number of
patients annually. Neurodegenerative diseases such as Alzheimer's disease and …

Many brain tumors and neurological diseases can greatly benefit from the use of emerging
nanotechnologies based on targeted nanomedicines that are able to noninvasively transport …

Nose-to-brain delivery is a promising approach to target drugs into the brain, avoiding the
blood-brain barrier and other drawbacks related to systemic absorption, and enabling an …

Brain delivery of drugs faces limitations due to the physiological and physical barriers. One
of the strategies to overcome this problem is the use of nanotechnology in a pharmaceutical …