An Endophytic Pseudonocardia Species Induces the Production of Artemisinin in Artemisia annua

J Li, GZ Zhao, A Varma, S Qin, Z Xiong, HY Huang… - PloS one, 2012 - journals.plos.org
Endophytic actinobacteria colonize internal tissues of their host plants and are considered
as a rich and reliable source of diverse species and functional microorganisms. In this study …

Endophytes in Artemisia annua L.: new potential regulators for plant growth and artemisinin biosynthesis

LP Zheng, XP Li, LL Zhou, JW Wang - Plant Growth Regulation, 2021 - Springer
The medicinal plant Artemisia annua L. is presently the sole plant source of artemisinin, the
key ingredient of first-line antimalarial drug. As the content of artemisinin in the native plant …

The influence of endophytic Penicillium oxalicum B4 on growth and artemisinin biosynthesis of in vitro propagated plantlets of Artemisia annua L.

LP Zheng, H Tian, YF Yuan, JW Wang - Plant Growth Regulation, 2016 - Springer
Artemisia annua L. is presently the sole natural source of antimalarial drug artemisinin. We
established dual cultures of A. annua callus or regenerated plantlets with endophytic …

Endophytic actinomycetes associated with Cinnamomum cassia Presl in Hoa Binh province, Vietnam: Distribution, antimicrobial activity and, genetic features

THN Vu, QH Nguyen, TML Dinh, NT Quach… - The Journal of General …, 2020 - jstage.jst.go.jp
For thousands of years, medicinal plants have widely been used as natural medicines in the
treatment of human diseases (Pan et al., 2014). Nevertheless, medicinal plants are also well …

Growth Promotion of Salicornia bigelovii by Micromonospora chalcea UAE1, an Endophytic 1-Aminocyclopropane-1-Carboxylic Acid Deaminase-Producing …

KA El-Tarabily, AS AlKhajeh, MM Ayyash… - Frontiers in …, 2019 - frontiersin.org
Salicornia bigelovii is a promising halophytic crop for saline soils in semi-arid regions. This
study was designed to characterize isolates of endophytic actinobacteria from S. bigelovii …

Promotion of artemisinin content in Artemisia annua by overexpression of multiple artemisinin biosynthetic pathway genes

P Shi, X Fu, M Liu, Q Shen, W Jiang, L Li, X Sun… - Plant Cell, Tissue and …, 2017 - Springer
Artemisinin, isolated from an annual herbaceous plant Artemisia annua L., is an effective
antimalarial compound. However, artemisinin is accumulated in small amounts (0.01–0.1 …

Isolation, abundance and phylogenetic affiliation of endophytic actinomycetes associated with medicinal plants and screening for their in vitro antimicrobial …

AK Passari, VK Mishra, R Saikia, VK Gupta… - Frontiers in …, 2015 - frontiersin.org
Microorganisms associated with medicinal plants are of interest as the producers of
important bioactive compounds. To date, the diversity of culturable endophytic …

Endophytic Actinomycetes from Azadirachta indica A. Juss.: Isolation, Diversity, and Anti-microbial Activity

VC Verma, SK Gond, A Kumar, A Mishra, RN Kharwar… - Microbial ecology, 2009 - Springer
Endophytic actinomycetes from Azadirachta indica A. Juss. were screened and evaluated for
their anti-microbial activity against an array of pathogenic fungi and bacteria. A total of 55 …

Effects of exogenous indole‐3‐acetic acid on the density of trichomes, expression of artemisinin biosynthetic genes, and artemisinin biosynthesis in Artemisia annua

Z Guo, Q Zhang, Y Zhang, C Wu… - Biotechnology and …, 2023 - Wiley Online Library
Artemisinin is the most practical medication for the treatment of malaria, but is only very
minimally synthesized in Artemisia annua, significantly less than the market needs. In this …

Phylogenetic affiliation of endophytic actinobacteria associated with selected orchid species and their role in growth promotion and suppression of phytopathogens

J Saikia, R Mazumdar, D Thakur - Frontiers in Plant Science, 2022 - frontiersin.org
Endophytic actinobacteria aid in plant development and disease resistance by boosting
nutrient uptake or producing secondary metabolites. For the first time, we investigated the …