Biomarkers in systemic lupus erythematosus: challenges and prospects for the future

CC Liu, AH Kao, S Manzi… - Therapeutic advances in …, 2013 - journals.sagepub.com
The search for lupus biomarkers to diagnose, monitor, stratify, and predict individual
response to therapy is currently more intense than ever before. This effort is essential for …

Biomarkers for systemic lupus erythematosus: a review and perspective

CC Liu, S Manzi, JM Ahearn - Current opinion in rheumatology, 2005 - journals.lww.com
There is a longstanding and recently rejuvenated enthusiasm for biomarkers that precisely
and specifically reflect the pathophysiologic and clinical changes in systemic lupus …

The search for lupus biomarkers

CC Liu, JM Ahearn - Best practice & research clinical rheumatology, 2009 - Elsevier
Few biomarkers for systemic lupus erythematosus (SLE) have been validated and employed
for making clinical decisions. The lack of reliable, specific biomarkers for SLE hampers the …

[引用][C] Biomarkers in systemic lupus erythematosus: I. General overview of biomarkers and their applicability

GG Illei, E Tackey, L Lapteva… - Arthritis & Rheumatism …, 2004 - Wiley Online Library
There is a high level of interest in the identification and validation of biomarkers that
precisely reflect specific aspects of systemic lupus erythematosus (SLE). Patients are hoping …

[引用][C] Biomarkers in systemic lupus erythematosus: II. Markers of disease activity

GG Illei, E Tackey, L Lapteva… - Arthritis & Rheumatism …, 2004 - Wiley Online Library
Systemic lupus erythematosus (SLE) is the most heterogeneous chronic autoimmune
disease. Biologic markers that reliably describe various aspects of SLE could be used to …

[HTML][HTML] Emerging molecular markers towards potential diagnostic panels for lupus

G Tan, B Baby, Y Zhou, T Wu - Frontiers in Immunology, 2022 - frontiersin.org
Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease which can affect
various tissues and organs, posing significant challenges for clinical diagnosis and …

Systemic lupus erythematosus biomarkers: the challenging quest

C Arriens, JD Wren, ME Munroe, C Mohan - Rheumatology, 2017 - academic.oup.com
SLE, a multisystem heterogeneous disease, is characterized by production of antibodies to
cellular components, with activation of both the innate and the adaptive immune system …

Biomarkers for systemic lupus erythematosus

JM Ahearn, CC Liu, AH Kao, S Manzi - Translational Research, 2012 - Elsevier
The urgent need for lupus biomarkers was demonstrated in September 2011 during a
Workshop sponsored by the Food and Drug Administration: Potential Biomarkers Predictive …

[HTML][HTML] Advanced methods and novel biomarkers in autoimmune diseases‑a review of the recent years progress in systemic lupus erythematosus

KA Fenton, HL Pedersen - Frontiers in Medicine, 2023 - ncbi.nlm.nih.gov
There are several autoimmune and rheumatic diseases affecting different organs of the
human body. Multiple sclerosis (MS) mainly affects brain, rheumatoid arthritis (RA) mainly …

Organ-specific biomarkers in lupus

H Wu, J Zeng, J Yin, Q Peng, M Zhao, Q Lu - Autoimmunity reviews, 2017 - Elsevier
Systemic lupus erythematosus (SLE) is a complex and highly heterogeneous disease, which
affects multiple organs, including joints, skin, kidneys, heart, hematopoietic system, and …