[HTML][HTML] Mechanisms and management of thyroid disease and atrial fibrillation: Impact of atrial electrical remodeling and cardiac fibrosis

A Takawale, M Aguilar, Y Bouchrit, R Hiram - Cells, 2022 - mdpi.com
Atrial fibrillation (AF) is the most common cardiac arrhythmia associated with increased
cardiovascular morbidity and mortality. The pathophysiology of AF is characterized by …

The bidirectional relationship of thyroid disease and atrial fibrillation: Established knowledge and future considerations

A Bekiaridou, A Kartas, DV Moysidis… - Reviews in Endocrine …, 2022 - Springer
Atrial fibrillation (AF) tends to occur frequently in patients with thyroid disease, primarily
hyperthyroidism. In hyperthyroidism, increased levels of thyroid hormones, via intra-and …

[HTML][HTML] Pro-arrhythmic signaling of thyroid hormones and its relevance in subclinical hyperthyroidism

N Tribulova, LH Kurahara, P Hlivak, K Hirano… - International Journal of …, 2020 - mdpi.com
A perennial task is to prevent the occurrence and/or recurrence of most frequent or life-
threatening cardiac arrhythmias such as atrial fibrillation (AF) and ventricular fibrillation (VF) …

Both hypothyroidism and hyperthyroidism increase atrial fibrillation inducibility in rats

Y Zhang, EI Dedkov, D Teplitsky… - Circulation …, 2013 - Am Heart Assoc
Background—Evidence indicates that cardiac hypothyroidism may contribute to heart failure
progression. It is also known that heart failure is associated with an increased risk of atrial …

New aspects of endocrine control of atrial fibrillation and possibilities for clinical translation

M Aguilar, RA Rose, A Takawale, S Nattel… - Cardiovascular …, 2021 - academic.oup.com
Hormones are potent endo-, para-, and autocrine endogenous regulators of the function of
multiple organs, including the heart. Endocrine dysfunction promotes a number of …

Mechanism and prevention of atrial remodeling and their related genes in cardiovascular disorders

B Sandeep, W Ding, X Huang, C Liu, Q Wu, X Su… - Current Problems in …, 2023 - Elsevier
Atrial fibrillation (AF) is associated with profound structural and functional changes in the
atrium. Inflammation mediated atrial fibrosis is one of the key mechanisms in the …

Cardiac arrhythmia and thyroid dysfunction: a novel genetic link

K Purtell, TK Roepke, GW Abbott - … journal of biochemistry & cell biology, 2010 - Elsevier
Inherited Long QT Syndrome (LQTS), a cardiac arrhythmia that predisposes to the often
lethal ventricular fibrillation, is commonly linked to mutations in KCNQ1. The KCNQ1 voltage …

[HTML][HTML] Atrial cardiomyopathy: pathophysiology and clinical consequences

A Goette, U Lendeckel - Cells, 2021 - mdpi.com
Around the world there are 33.5 million patients suffering from atrial fibrillation (AF) with an
annual increase of 5 million cases. Most AF patients have an established form of an atrial …

Atrial remodeling, fibrosis, and atrial fibrillation

J Jalife, K Kaur - Trends in cardiovascular medicine, 2015 - Elsevier
The fundamental mechanisms governing the perpetuation of atrial fibrillation (AF), the most
common arrhythmia seen in clinical practice, are poorly understood, which explains in part …

Inflammatory pathways underlying atrial fibrillation

K Friedrichs, A Klinke, S Baldus - Trends in molecular medicine, 2011 - cell.com
The pathophysiology of atrial fibrillation (AF) remains incompletely understood, despite its
prevalence and contributing role in stroke and heart failure. Whereas previous studies have …