Cholinergic transmission regulates many behavioural domains, ranging from motor activity
to cognition. Acetylcholine signalling is mediated by muscarinic and nicotinic acetylcholine …

Acetylcholine is an important modulator of striatal activity, and it is vital to controlling striatal-
dependent behaviors, including motor and cognitive functions. Despite this significance, the …

Nicotinic acetylcholine receptors (nAChRs) are widely expressed in the central nervous
system and play an important role in the control of neural functions including neuronal …

The cholinergic system is one of the most influential and essential signalling systems in the
body. In the brain, cholinergic neurons innervate many brain regions where they influence a …

The focus of this CTBN volume aims to provide an overview of cholinergic systems in
relation to their effects on behavior and disease. Our intent was to organize a broad series of …

Acetylcholine (ACh) is a known modulator of the activity of dopaminergic (DAergic) neurons
through the stimulation of nicotinic ACh receptors (nAChRs). Yet, the subunit composition …

While historically acetylcholine (ACh) holds a central place in the discovery of chemical
transmission in the nervous system, progress in our knowledge of the mechanistic …

Research over the last 15 years supports the need for a revision of long-held theories
surrounding the function of the brain cholinergic systems (Figure 1). Historically described …

Acetylcholine (ACh) signaling shapes neuronal circuit development and underlies specific
aspects of cognitive functions and behaviors, including attention, learning, memory and …

Nicotinic acetylcholine receptors (nAChRs) are widely expressed in midbrain dopamine
neurons that project to dorsal striatum, nucleus accumbens and prefrontal cortex. Thus …