Recently, a new regulatory circuitry has been identified in which RNAs can crosstalk with
each other by competing for shared microRNAs. Such competing endogenous RNAs …

A fundamental process during both embryo development and stem cell differentiation is the
control of cell lineage determination. In developing skeletal muscle, many of the diffusible …

The muscle-specific long noncoding RNA linc-MD1 was shown to be expressed during early
phases of muscle differentiation and to trigger the switch to later stages by acting as a …

Deciphering the mechanisms underlying skeletal muscle-cell differentiation in mammals is
an important challenge. Cell differentiation involves complex pathways regulated at both …

Vertebrate muscle differentiation is coordinated by an intricate network of transcription
factors requiring proliferating myogenic precursors to withdraw irreversibly from the cell …

Three muscle-specific microRNAs, miR-206,-1, and-133, are induced during differentiation
of C2C12 myoblasts in vitro. Transfection of miR-206 promotes differentiation despite the …

Increasing evidence suggests that long non-coding RNAs (LncRNAs) represent a new class
of regulators of stem cells. However, the roles of LncRNAs in stem cell maintenance and …

Unique expression domains, targets, and gain-and loss-of-function phenotypes of particular
microRNAs have important implications for directed differentiation of stem cell populations …

MicroRNAs (miRNAs) have emerged as critical regulators of numerous biological processes
by modulating gene expression at the post-transcriptional level. It has become increasingly …

microRNAs (miRNAs) are 21–23-nucleotide non-coding RNAs. It has become more and
more evident that this class of small RNAs plays critical roles in the regulation of gene …