Detection of 140 clinically relevant antibiotic-resistance genes in the plasmid metagenome of wastewater treatment plant bacteria showing reduced susceptibility to …

R Szczepanowski, B Linke, I Krahn… - …, 2009 - microbiologyresearch.org
To detect plasmid-borne antibiotic-resistance genes in wastewater treatment plant (WWTP)
bacteria, 192 resistance-gene-specific PCR primer pairs were designed and synthesized …

Host range of antibiotic resistance genes in wastewater treatment plant influent and effluent

J Hultman, M Tamminen, K Pärnänen… - FEMS microbiology …, 2018 - academic.oup.com
Wastewater treatment plants (WWTPs) collect wastewater from various sources for a multi-
step treatment process. By mixing a large variety of bacteria and promoting their proximity …

Exploring antibiotic resistance genes and metal resistance genes in plasmid metagenomes from wastewater treatment plants

AD Li, LG Li, T Zhang - Frontiers in microbiology, 2015 - frontiersin.org
Plasmids operate as independent genetic elements in microorganism communities. Through
horizontal gene transfer (HGT), they can provide their host microorganisms with important …

Insight into the plasmid metagenome of wastewater treatment plant bacteria showing reduced susceptibility to antimicrobial drugs analysed by the 454 …

R Szczepanowski, T Bekel, A Goesmann… - Journal of …, 2008 - Elsevier
Wastewater treatment plants (WWTPs) are a reservoir for bacteria harbouring antibiotic
resistance plasmids. To get a comprehensive overview on the plasmid metagenome of …

Characterization of metagenomes in urban aquatic compartments reveals high prevalence of clinically relevant antibiotic resistance genes in wastewaters

C Ng, M Tay, B Tan, TH Le, L Haller, H Chen… - Frontiers in …, 2017 - frontiersin.org
The dissemination of antimicrobial resistance (AMR) is an escalating problem and a threat to
public health. Comparative metagenomics was used to investigate the occurrence of …

Fate and proliferation of typical antibiotic resistance genes in five full-scale pharmaceutical wastewater treatment plants

J Wang, D Mao, Q Mu, Y Luo - Science of the Total Environment, 2015 - Elsevier
This study investigated the characteristics of 10 subtypes of antibiotic resistance genes
(ARGs) for sulfonamide, tetracycline, β-lactam and macrolide resistance and the class 1 …

Genetic diversity and composition of a plasmid metagenome from a wastewater treatment plant

A Schlüter, L Krause, R Szczepanowski… - Journal of …, 2008 - Elsevier
Plasmid metagenome nucleotide sequence data were recently obtained from wastewater
treatment plant (WWTP) bacteria with reduced susceptibility to selected antimicrobial drugs …

Abundance of antibiotic resistance genes in five municipal wastewater treatment plants in the Monastir Governorate, Tunisia

ID Rafraf, I Lekunberri, A Sànchez-Melsió, M Aouni… - Environmental …, 2016 - Elsevier
Antimicrobial resistance is a growing and significant threat to global public health, requiring
better understanding of the sources and mechanisms involved in its emergence and spread …

[HTML][HTML] Functional metagenomic analysis reveals rivers are a reservoir for diverse antibiotic resistance genes

GCA Amos, L Zhang, PM Hawkey, WH Gaze… - Veterinary …, 2014 - Elsevier
The environment harbours a significant diversity of uncultured bacteria and a potential
source of novel and extant resistance genes which may recombine with clinically important …

Identification of diverse antimicrobial resistance determinants carried on bacterial, plasmid, or viral metagenomes from an activated sludge microbial assemblage

LC Parsley, EJ Consuegra, KS Kakirde… - Applied and …, 2010 - Am Soc Microbiol
Using both sequence-and function-based metagenomic approaches, multiple antibiotic
resistance determinants were identified within metagenomic libraries constructed from DNA …