Simple Summary Omega-3 fatty acids are vital for optimal fetal and placental development.
Under conditions of oxidative stress, toxic by-products called lipid aldehydes are produced …

Pregnancy represents a state of heightened oxidative stress and inflammation, and these
processes are further increased in pregnancy complications. The quality of the maternal diet …

Placental oxidative stress plays a key role in the pathophysiology of several placenta-related
disorders including intrauterine growth restriction. Oxidative stress occurs when …

Certain limitations exist for animals to modify fatty acid changes. Besides the role of
arachidonic acid (AA), docosahexaenoic acid (DHA) and other 20-carbon long-chain …

Normal pregnancy relies on inflammation for implantation, placentation, and parturition, but
uncontrolled inflammation can lead to poor maternal and infant outcomes. Maternal diet is …

Air pollution is detrimental to pregnancy adversely affecting maternal and child health. Our
objective was to unravel epigenetic mechanisms mediating the effect of pre-conception …

abstract Background: The placentas of obese women accumulate lipids that may alter fetal
lipid exposure. The long-chain omega-3 fatty acids (n–3 FAs) docosahexaenoic acid (DHA) …

The developing fetus requires substantial amounts of fatty acids to support rapid cellular
growth and activity. Although the fatty acid composition delivered to the fetus is largely …

Docosahexaenoic acid (DHA) supplementation in pregnancy may confer some clinical
benefits; however, this compound can exert pro-oxidant effects. In this study, we investigated …

Introduction Placentas of obese women have higher lipid content compared to lean women.
We have previously shown that supplementation of overweight and obese women with …