Elucidating the transcribed regions of the genome constitutes a fundamental aspect of
human biology, yet this remains an outstanding problem. To comprehensively identify …

Recently, we mapped the sites of transcription across∼ 30% of the human genome and
elucidated the structures of several hundred novel transcripts. In this report, we describe a …

Explores several studies on the complexity of the human transcriptome. Use of tiling arrays
to identify transcribed fragments of the human genome; Emphasis of transcriptome analysis …

Transcriptomic analyses have revealed an unexpected complexity to the human
transcriptome, whose breadth and depth exceeds current RNA sequencing capability …

Using a maskless photolithography method, we produced DNA oligonucleotide microarrays
with probe sequences tiled throughout the genome of the plant Arabidopsis thaliana. RNA …

The most important product of the sequencing of a genome is a complete, accurate
catalogue of genes and their products, primarily messenger RNA transcripts and their …

Microarrays have become a popular and important technology for surveying global patterns
in gene expression and regulation. A number of innovative experiments have extended …

The identification of untranslated regions, introns, and coding regions within an organism
remains challenging. We developed a quantitative sequencing-based method called RNA …

Background Computational and microarray-based experimental approaches were used to
generate a comprehensive transcript index for the human genome. Oligonucleotide probes …

Global RNA studies have become central to understanding biological processes, but
methods such as microarrays and short-read sequencing are unable to describe an entire …