Counterions are vital for the structure and function of biomolecules. However, the behavior
of counterions remains elusive due to the difficulty in characterizing mobile ions. Here, we …

Counterions are important constituents for the structure and function of nucleic acids. Using
7 Li and 133 Cs nuclear magnetic resonance (NMR) spectroscopy, we investigated how …

Due to a high density of negative charges on its surface, DNA condenses cations as
counterions, forming the so‐called “ion atmosphere”. Although the release of counterions …

In this work, a novel NMR method for the identification of preferential coordination sites
between physiologically relevant counterions and nucleic acid bases is demonstrated. In …

Conspectus Molecular association of proteins with nucleic acids is required for many
biological processes essential to life. Electrostatic interactions via ion pairs (salt bridges) of …

Sodium ions are essential for the functions of biological cells, and they are maintained at the
balance between intra-and extracellular environments. The quantitative assessment of intra …

Electrostatic potentials around macromolecules in the presence of mobile charges are
difficult to assess especially for highly charged systems. Here, we report measurements of …

We have developed a novel method to study the interactions of nucleic acids with cationic
species. The method, called phosphorus relaxation enhancement (PhoRE), uses 1H …

Ion pairing is one of the most fundamental chemical interactions and is essential for
molecular recognition by biological macromolecules. From an experimental standpoint, very …

Jorgen Dinesen and Jens Peter Jacobsen* Department of Chemistry, Odense University,
Campusvej 55, DK-5230 Odense M, Denmark Received September 8, 1988; Revised …