Treatment of breast cancer through the application of irreversible electroporation using a novel minimally invasive single needle electrode

RE Neal, R Singh, HC Hatcher, ND Kock… - Breast cancer research …, 2010 - Springer
Irreversible electroporation (IRE) is a therapeutic technology for the ablation of soft tissues
using electrodes to deliver intense but short electric pulses across a cell membrane, creating …

The feasibility of irreversible electroporation for the treatment of breast cancer and other heterogeneous systems

RE Neal, RV Davalos - Annals of biomedical engineering, 2009 - Springer
Developments in breast cancer therapies show potential for replacing simple and radical
mastectomies with less invasive techniques. Localized thermal techniques encounter …

Tumor ablation with irreversible electroporation

B Al-Sakere, F André, C Bernat, E Connault, P Opolon… - PloS one, 2007 - journals.plos.org
We report the first successful use of irreversible electroporation for the minimally invasive
treatment of aggressive cutaneous tumors implanted in mice. Irreversible electroporation is a …

Tissue heterogeneity in structure and conductivity contribute to cell survival during irreversible electroporation ablation by “electric field sinks”

A Golberg, BG Bruinsma, BE Uygun, ML Yarmush - Scientific reports, 2015 - nature.com
Irreversible electroporation (IRE) is an emerging, minimally invasive technique for solid
tumors ablation, under clinical investigation for cancer therapy. IRE affects only the cell …

Mathematical modeling of irreversible electroporation for treatment planning

JF Edd, RV Davalos - Technology in cancer research & …, 2007 - journals.sagepub.com
Irreversible Electroporation (IRE) is a new drug-free method to ablate undesirable tissue of
particular use in cancer therapy. IRE achieves cell death within the targeted tissue through a …

Successful treatment of a large soft tissue sarcoma with irreversible electroporation

RE Neal, JH Rossmeisl Jr, PA Garcia… - Journal of Clinical …, 2011 - ascopubs.org
Irreversible electroporation (IRE) is a promising technique for the focal treatment of
pathologic tissues that involves placing minimally invasive electrodes within the targeted …

Tissue ablation with irreversible electroporation

RV Davalos, LM Mir, B Rubinsky - Annals of biomedical engineering, 2005 - Springer
This study introduces a new method for minimally invasive treatment of cancer—the ablation
of undesirable tissue through the use of irreversible electroporation. Electroporation is the …

Membrane-targeting approaches for enhanced cancer cell destruction with irreversible electroporation

C Jiang, Z Qin, J Bischof - Annals of biomedical engineering, 2014 - Springer
Irreversible electroporation (IRE) is a promising technology to treat local malignant cancer
using short, high-voltage electric pulses. Unfortunately, in vivo studies show that IRE suffers …

Introduction to irreversible electroporation—principles and techniques

KR Thomson, H Kavnoudias, RE Neal II - Techniques in vascular and …, 2015 - Elsevier
Irreversible electroporation (IRE) is a novel nonthermal focal ablation technique that uses a
series of brief but intense electric pulses delivered by paired electrodes into a targeted …

Towards solid tumor treatment by irreversible electroporation: intrinsic redistribution of fields and currents in tissue

AT Esser, KC Smith… - … in cancer research & …, 2007 - journals.sagepub.com
Local and drug-free tissue treatment by irreversible electroporation (IRE) involves the
creation of aqueous pores in a cell's plasma membrane (PM) and leads to non-thermal cell …