[HTML][HTML] Critical Roles of the Circadian Transcription Factor BMAL1 in Reproductive Endocrinology and Fertility
Y Jiang, S Li, W Xu, J Ying, Y Qu, X Jiang… - Frontiers in …, 2022 - frontiersin.org
Brain and muscle aryl-hydrocarbon receptor nuclear translocator like protein1 (BMAL1), a
core component of circadian oscillation, is involved in many physiological activities …
core component of circadian oscillation, is involved in many physiological activities …
Loss of Bmal1 decreases oocyte fertilization, early embryo development and implantation potential in female mice
J Xu, Y Li, Y Wang, Y Xu, C Zhou - Zygote, 2016 - cambridge.org
Biological clock genes expressed in reproductive tissues play important roles in maintaining
the normal functions of reproductive system. However, disruption of female circadian rhythm …
the normal functions of reproductive system. However, disruption of female circadian rhythm …
Impaired Steroidogenesis and Implantation Failure in Bmal1−/− Mice
CK Ratajczak, KL Boehle, LJ Muglia - Endocrinology, 2009 - academic.oup.com
Evidence in humans and rodents suggests that normal circadian rhythmicity is important for
supporting reproductive function. A molecular clock underlies circadian rhythmicity. Impaired …
supporting reproductive function. A molecular clock underlies circadian rhythmicity. Impaired …
[HTML][HTML] Core clock gene Bmal1 deprivation impairs steroidogenesis in mice luteinized follicle cells
Y Wang, M Chen, J Xu, X Liu, Y Duan, C Zhou… - …, 2020 - rep.bioscientifica.com
Luteinization is the event of corpus luteum formation, a way of follicle cells transformation
and a process of steroidogenesis alteration. As the core clock gene, Bmal1 was involved in …
and a process of steroidogenesis alteration. As the core clock gene, Bmal1 was involved in …
[HTML][HTML] The circadian clock, nutritional signals and reproduction: a close relationship
M Ono, H Ando, T Daikoku, T Fujiwara… - International journal of …, 2023 - mdpi.com
The circadian rhythm, which is necessary for reproduction, is controlled by clock genes. In
the mouse uterus, the oscillation of the circadian clock gene has been observed. The …
the mouse uterus, the oscillation of the circadian clock gene has been observed. The …
The circadian clock protein BMAL1 is necessary for fertility and proper testosterone production in mice
JD Alvarez, A Hansen, T Ord, P Bebas… - Journal of biological …, 2008 - journals.sagepub.com
Although it is well established that the circadian clock regulates mammalian reproductive
physiology, the molecular mechanisms by which this regulation occurs are not clear. The …
physiology, the molecular mechanisms by which this regulation occurs are not clear. The …
Downregulation of core clock gene Bmal1 attenuates expression of progesterone and prostaglandin biosynthesis-related genes in rat luteinizing granulosa cells
Ovarian circadian oscillators have been implicated in the reproductive processes of
mammals. However, there are few reports regarding the detection of ovarian clock …
mammals. However, there are few reports regarding the detection of ovarian clock …
Bmal1 is required for normal reproductive behaviors in male mice
EL Schoeller, DD Clark, S Dey, NV Cao… - …, 2016 - academic.oup.com
Circadian rhythms synchronize physiological processes with the light-dark cycle and are
regulated by a hierarchical system initiated in the suprachiasmatic nucleus, a hypothalamic …
regulated by a hierarchical system initiated in the suprachiasmatic nucleus, a hypothalamic …
Generation of myometrium-specific Bmal1 knockout mice for parturition analysis
CK Ratajczak, M Asada, GC Allen… - Reproduction …, 2012 - CSIRO Publishing
Human and rodent studies indicate a role for circadian rhythmicity and associated clock
gene expression in supporting normal parturition. The importance of clock gene expression …
gene expression in supporting normal parturition. The importance of clock gene expression …
Conditional Deletion of Bmal1 in Ovarian Theca Cells Disrupts Ovulation in Female Mice
Rhythmic events in female reproductive physiology, including ovulation, are tightly
controlled by the circadian timing system. The molecular clock, a feedback loop oscillator of …
controlled by the circadian timing system. The molecular clock, a feedback loop oscillator of …