Streptococcus pneumoniae is a leading cause of pneumonia and meningitis worldwide.
Many different serotypes co-circulate endemically in any one location,. The extent and …

Resistance of Streptococcus pneumoniae to antibiotics is increasing throughout the United
States, with substantial variation among geographic regions. We show that patterns of …

Evasion of clinical interventions by Streptococcus pneumoniae occurs through selection of
non-susceptible genomic variants. We report whole-genome sequencing of 3,085 …

We carried out multilocus sequence typing (MLST) on 148 pneumococcal carriage isolates
collected from children< 24 months old in the Upper River Division, the Gambia. MLST …

Whole-genome sequencing of 616 asymptomatically carried Streptococcus pneumoniae
isolates was used to study the impact of the 7-valent pneumococcal conjugate vaccine …

Genomic evolution, transmission and pathogenesis of Streptococcus pneumoniae, an
opportunistic human-adapted pathogen, is driven principally by nasopharyngeal carriage …

Understanding how pathogens spread across geographical space is fundamental for control
measures such as vaccination. Streptococcus pneumoniae (the pneumococcus) is a …

Streptococcus pneumoniae (the pneumococcus) is a globally distributed, human obligate
opportunistic bacterial pathogen which, although often carried commensally, is also a …

We carried out multilocus sequence typing (MLST) on 148 pneumococcal carriage isolates
collected from children< 24 months old in the Upper River Division, the Gambia. MLST …

The transmission dynamics of Streptococcus pneumoniae in sub-Saharan Africa are poorly
understood due to a lack of adequate epidemiological and genomic data. Here we leverage …