Patterned cell and matrix dynamics in branching morphogenesis

S Wang, R Sekiguchi, WP Daley, KM Yamada - Journal of Cell Biology, 2017 - rupress.org
Many embryonic organs undergo branching morphogenesis to maximize their functional
epithelial surface area. Branching morphogenesis requires the coordinated interplay of …

Branching morphogenesis

K Goodwin, CM Nelson - Development, 2020 - journals.biologists.com
Over the past 5 years, several studies have begun to uncover the links between the classical
signal transduction pathways and the physical mechanisms that are used to sculpt branched …

Extracellular matrix and cytoskeletal dynamics during branching morphogenesis

HY Kim, CM Nelson - Organogenesis, 2012 - Taylor & Francis
Branching morphogenesis is a fundamental developmental process which results in
amplification of epithelial surface area for exchanging molecules in organs including the …

Cellular and physical mechanisms of branching morphogenesis

VD Varner, CM Nelson - Development, 2014 - journals.biologists.com
Branching morphogenesis is the developmental program that builds the ramified epithelial
trees of various organs, including the airways of the lung, the collecting ducts of the kidney …

Spatially coordinated cell cycle activity and motility govern bifurcation of mammary branches

SM Myllymäki, B Kaczyńska, Q Lan… - Journal of Cell Biology, 2023 - rupress.org
Branching morphogenesis is an evolutionary solution to maximize epithelial function in a
compact organ. It involves successive rounds of branch elongation and branch point …

Tissue remodelling through branching morphogenesis

M Affolter, R Zeller, E Caussinus - Nature reviews Molecular cell biology, 2009 - nature.com
Branched structures are evident at all levels of organization in living organisms. Many
organs, such as the vascular system, lung, kidney and mammary gland, are heavily …

Cell and fibronectin dynamics during branching morphogenesis

M Larsen, C Wei, KM Yamada - Journal of cell science, 2006 - journals.biologists.com
Branching morphogenesis is a dynamic developmental process shared by many organs, but
the mechanisms that reorganize cells during branching morphogenesis are not well …

Organ-specific branching morphogenesis

C Lang, L Conrad, D Iber - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
A common developmental process, called branching morphogenesis, generates the
epithelial trees in a variety of organs, including the lungs, kidneys, and glands. How …

Branching morphogenesis: from cells to organs and back

A Ochoa-Espinosa, M Affolter - Cold Spring Harbor …, 2012 - cshperspectives.cshlp.org
Many animal organs, such as the lung, the kidney, the mammary gland, and the vasculature,
consist of branched tubular structures that arise through a process known as “branching …

Sculpting organs: mechanical regulation of tissue development

CM Nelson, JP Gleghorn - Annual review of biomedical …, 2012 - annualreviews.org
The ramified architectures of organs such as the mammary gland and lung are generated
via branching morphogenesis, a developmental process through which individual cells bud …