A novel hydrophobic chitosan derivative, octanoyl chitosan (OC) with improved organic
solubility was synthesized, characterized, and employed for the preparation of rifampicin …

The aim of current study was to illustrate a strategy to encapsulate itraconazole into chitosan-
based nanoparticles using a modified ionic gelation method and to fabricate them as …

Background: The lung is the primary entry site and target for Mycobacterium tuberculosis;
more than 80% of the cases reported worldwide are of pulmonary tuberculosis. Hence …

Current treatment therapeutic approach for tuberculosis is the administration of first line
drugs in the form of tablets and capsules for 4–6 months. However, this approach leads to …

This study reports the development of nanoparticles in the form of inhalable micro-
aggregates of biodegradable chitosan (CS) loaded with nicotine hydrogen tartrate (NHT) for …

In this study, nanocrystals embedded in microparticles were designed to achieve sustained
pulmonary drug delivery of hydrophobic drugs. Chitosan based microparticles were …

The aim of this study was to prepare and characterize spray dried inhalable chitosan
nanoparticles (CNPs) for sustained delivery of anti-tubercular drugs, isoniazid (INH) and …

This study aimed to prepare and evaluate rifampicin microparticles for the lung delivery of
rifampicin as respirable powder. The microparticles were prepared using chitosan by the …

The aim of this study was to prepare spray dried inhalable powders containing isoniazid-
loaded chitosan/tripolyphosphate (TPP) nanoparticles for sustained delivery of the drug to …

This study aimed to design dry powder inhaler formulations using a hydrophilic polymeric
polysaccharide, phytoglycogen (PyG), as a multi-functional additive that increases the …