Current management of CML patients: Summary of the Italian Consensus Meeting held in Rome, April 11–12, 2013

M Breccia, G Alimena, M Baccarani, M Bocchia… - Critical Reviews in …, 2014 - Elsevier
Abstract Treatment of Chronic Myeloid Leukaemia (CML) has evolved rapidly in the last 10
years. The objectives of this national consensus meeting were to describe the optimal …

On the road to treatment-free remission in chronic myeloid leukemia: what about 'the others'?

F Stagno, M Breccia, F Di Raimondo - Expert Review of Anticancer …, 2020 - Taylor & Francis
Introduction The treatment of chronic myeloid leukemia (CML) has been drastically changed
by the approval of tyrosine kinase inhibitors (TKIs). CML is now managed as a chronic …

The concept of treatment-free remission in chronic myeloid leukemia

S Saußele, J Richter, A Hochhaus, FX Mahon - Leukemia, 2016 - nature.com
The advent of tyrosine kinase inhibitors (TKI) into the management of patients with chronic
myeloid leukemia (CML) has profoundly improved prognosis. Survival of responders is …

Treatment-free remission in CML: who, how, and why?

FX Mahon - Hematology 2014, the American Society of …, 2017 - ashpublications.org
Chronic myeloid leukemia (CML) is the best example of successful targeted therapy. Today,
the overall survival of patients with CML treated by using tyrosine kinase inhibitors (TKIs) is …

Treatment-free remission in chronic myeloid leukemia.

M Molica, K Naqvi, JE Cortes, S Paul… - Clinical Advances in …, 2019 - europepmc.org
Tyrosine kinase inhibitors (TKIs) represent a major breakthrough in the treatment of chronic
myeloid leukemia (CML). Thanks to these agents, CML has been transformed from a …

Update on current monitoring recommendations in chronic myeloid leukemia: practical points for clinical practice

VG Oehler - Hematology 2013, the American Society of …, 2013 - ashpublications.org
Excellent therapeutic options exist for the treatment of chronic-phase chronic myeloid
leukemia (CML) patients. Therefore, managing CML patients has become a more common …

Diagnostic algorithms, monitoring, prognostication, and therapy in chronic myeloid leukemia (CML): a proposal of the Austrian CML platform.

P Valent, T Lion, D Wolf, C Sillaber, H Agis… - Wiener Klinische …, 2008 - europepmc.org
Chronic myeloid leukemia (CML) is a stem cell disease characterized by the BCR/ABL
oncoprotein. The ABL kinase inhibitor imatinib is effective in most patients and considered …

[HTML][HTML] The Target UK study: Real-world evidence of molecular response to tyrosine kinase inhibitors supports European LeukemiaNet 2013 recommendations for …

D Milojkovic, RE Clark, JL Byrne, BJP Huntly… - Blood, 2017 - Elsevier
Introduction: Several recent studies have shown the speed and depth of response to
tyrosine kinase inhibitor (TKI) treatment to be an important indicator of patient outcomes in …

Chronic myeloid leukemia: what is the best strategy to start and monitor treatment outside academic centers?

C Pavlovsky, MJ Mela Osorio - Current Oncology Reports, 2018 - Springer
The introduction of tyrosine kinase inhibitors (TKI) has dramatically changed the outcome of
chronic myeloid leukemia (CML). Over the last decade, imatinib positioned itself as the gold …

[HTML][HTML] FINAL analysis of a PAN European STOP tyrosine kinase inhibitor trial in chronic myeloid leukemia: the EURO-SKI study

FX Mahon, J Richter, A Hochhaus, P Panayiotidis… - Blood, 2021 - Elsevier
Background: With the dramatic success of tyrosine kinase inhibitors (TKI) to treat Chronic
myeloid leukemia (CML), the life expectancy of CML patients is now close to that of the …