The appearance, the odor, and the flavor of foods, all send messages to the encephalic area
of the brain. The hypothalamus, in particular, plays a key role in the mechanisms that control …

This paper reviews the involvement of the serotonergic system in controlling food intake and
satiety. It is of great interest to understand this system relevance in physiologic control of …

Recent pharmacological studies have more precisely characterised the nature of the
inhibitory effect of brain serotonin (5-hydroxytryptamine) on feeding behaviour. Thus, the …

There is an intimate relationship between nutritional intake (eating) and serotonin activity.
Experimental manipulations (mainly neuropharmacological) of serotonin influence the …

Brain serotonin appears to be an excellent target for designing drugs to treat obesity. The
prototype drug dexfenfluramine accelerates the onset of satiety and suppresses …

The role of serotonin in food intake has been studied for decades. Food intake is mainly
regulated by two brain circuitries:(i) the homeostatic circuitry, which matches energy intake …

Abstract Serotonin (5-HT), a mono-aminergic neurotransmitter is biochemically derived from
tryptophan and is mainly found in gastrointestinal tract, platelets and central nervous system …

Serotonin has been implicated in the control of satiety for almost four decades. Historically,
the insight that the appetite suppressant effect of fenfluramine is linked to serotonin has …

This paper reviews the evidence of serotoninergic mechanisms in human feeding by
considering the effects of 5-HT agonists, precursors and receptor antagonists on hunger …

Three decades on from Blundell's suggestion that serotonin serves to orchestrate
endogenous satiety, we present an overview of the behavioral, pharmacological and …