Background Gastrointestinal mucositis occurs as a consequence of cytotoxic treatment.
Quercetin (QCT) is a bioflavonoid that exerts significant antioxidant activity and anti …

Objective: The purpose of this experimental study was to evaluate the efficacy of carvacrol
(CVR) and pomegranate (PMG) against methotrexate (MTX)-induced intestinal damage …

The aim of this study was to analyze the influence of quercetin on intestinal barrier function
using the human colonic epithelial cell line HT‐29/B6 and rat small and large intestine in …

The long-term clinical use of methotrexate (MTX) is restricted due to its severe intestinal
toxicity. The protective effect of ginger or propolis on the toxicity induced by MTX is relatively …

Background/Aims: The objective of this study was to evaluate the effects of oral glutamine in
preventing intestinal mucosal damage caused by methotrexate (MTX) in rats. Methods: Male …

Methotrexate (MTX) is widely used in treatment of malignant tumors and autoimmune
diseases. Gastrointestinal toxicity is an important factor limiting its use. This study was …

Several studies have well confirmed the contribution of oxidative stress in the pathogenesis
of methotrexate (MTX)-induced damage in the small intestine. Many agents have been tried …

Purpose Orally administered rutin reportedly ameliorates 2, 4, 6-trinitrobenzene sulfonic acid
(TNBS)-induced colitis of rats. We investigated the metabolic and pharmacological …

Reactive oxygen species has been implicated to contribute significantly to tissue injury
associated with ulcerative colitis. Thus compounds with antioxidant properties could be …

Background and Objectives: Quercetin, a member of the flavanol family found in many fruits,
vegetables, leaves and grains has been found to have a wide range of biological effects on …