The mechanism underlying the ncRNA dysregulation pattern in hepatocellular carcinoma and its tumor microenvironment

C Xue, X Gu, Z Bao, Y Su, J Lu, L Li - Frontiers in immunology, 2022 - frontiersin.org
HCC is one of the most common malignant tumors and has an extremely poor prognosis.
Accumulating studies have shown that noncoding RNA (ncRNA) plays an important role in …

Non-coding RNAs in hepatocellular carcinoma: Insights into regulatory mechanisms, clinical significance, and therapeutic potential

Q Han, M Wang, X Dong, F Wei, Y Luo… - Frontiers in …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is a complex and heterogeneous malignancy with high
incidence and poor prognosis. In addition, owing to the lack of diagnostic and prognostic …

The role of long non-coding RNA and microRNA networks in hepatocellular carcinoma and its tumor microenvironment

T Shi, A Morishita, H Kobara, T Masaki - International journal of molecular …, 2021 - mdpi.com
Hepatocellular carcinoma (HCC) is a common liver malignancy with high morbidity and poor
prognosis. Long non-coding RNAs (lncRNAs) are involved in crucial biological processes of …

Noncoding RNA-mediated macrophage and cancer cell crosstalk in hepatocellular carcinoma

Z Zhou, Z Wang, J Gao, Z Lin, Y Wang, P Shan… - Molecular Therapy …, 2022 - cell.com
The tumor microenvironment (TME) is a well-recognized system that plays an essential role
in tumor initiation, development, and progression. Intense intercellular communication …

Decoding hepatocarcinogenesis from a noncoding RNAs perspective

MKA El‐Aziz, A Dawoud, CJ Kiriacos… - Journal of cellular …, 2023 - Wiley Online Library
Being a leading lethal malignancy worldwide, the pathophysiology of hepatocellular
carcinoma (HCC) has gained a lot of interest. Yet, underlying mechanistic basis of the liver …

The role of competing endogenous RNA network in the development of hepatocellular carcinoma: potential therapeutic targets

Z Tang, X Li, Y Zheng, J Liu, C Liu, X Li - Frontiers in Cell and …, 2024 - frontiersin.org
The current situation of hepatocellular carcinoma (HCC) management is challenging due to
its high incidence, mortality, recurrence and metastasis. Recent advances in gene genetic …

[HTML][HTML] Role of long noncoding RNA-mediated competing endogenous RNA regulatory network in hepatocellular carcinoma

ZS Niu, WH Wang, XN Dong - World journal of gastroenterology, 2020 - ncbi.nlm.nih.gov
Long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) are noncoding RNAs
(ncRNAs) that occupy over 90% of the human genome, and their main function is to directly …

Long non-coding RNAs as mediators of tumor microenvironment and liver cancer cell communication

YH Lin, MH Wu, CT Yeh, KH Lin - International Journal of Molecular …, 2018 - mdpi.com
The tumor microenvironment is an important concept that defines cancer development not
only through tumor cells themselves but also the surrounding cellular and non-cellular …

Role of non-coding RNAs in hepatocellular carcinoma progression: from classic to novel clinicopathogenetic implications

M Romeo, M Dallio, F Scognamiglio, L Ventriglia… - Cancers, 2023 - mdpi.com
Simple Summary Given the increasing incidence of hepatocellular carcinoma (HCC)
worldwide, a full comprehension of the molecular pathways supporting HCC onset and …

The emerging roles of non-coding competing endogenous RNA in hepatocellular carcinoma

G Xu, WY Xu, Y Xiao, B Jin, SD Du, Y Mao… - Cancer Cell …, 2020 - Springer
Accumulating evidence has emerged revealing that noncoding RNAs (ncRNAs) play
essential roles in the occurrence and development of hepatocellular carcinoma (HCC) …