3. Admon R, Nickerson LD, Dillon DG, Holmes AJ, Bogdan R, Kumar P, et al.(In Press).
Dissociable cortico-striatal connectivity abnormalities in major depression in response to …

Genome-wide association studies (GWAS) indicate neuropsychiatric disorders to be highly
polygenic. Polygenicity refers to the additive influence of multiple genes on variation in a …

Comments on an article by Maxwell L. Elliott et al.(see record 2018-24000-001). Elliott et
al.'s elegant exploration of the connectomic signature of the p factor demonstrates the …

A single dimension of general psychopathology, p, has been hypothesized to represent a
general liability that spans multiple types of psychiatric disorders and non-clinical variation …

Psychiatric disorders are phenotypically heterogeneous entities with a complex genetic
basis. To mitigate this complexity, many investigators study so-called intermediate …

Mental conditions exhibit a higher-order transdiagnostic factor structure which helps to
explain the widespread comorbidity observed in psychopathology. However, the phenotypic …

Psychiatric disorders have a complex biological underpinning likely involving an interplay of
genetic and environmental risk contributions. Substantial efforts are being made to use …

Genetic characterization of psychiatric disorders transcends diagnostic boundaries,
suggesting substantial pleiotropy of contributing genes. Indeed, recent large-scale genome …

Most neuropsychiatric disorders are highly polygenic, implicating hundreds to thousands of
causal genetic variants that span much of the genome. This widespread polygenicity …