We previously described the expression of CD36 and LPL by breast cancer (BC) cells and
tissues and the growth-promoting effect of VLDL observed only in the presence of LPL. We …

We previously described a lipid-accumulating phenotype of estrogen receptor negative
(ER−) breast cancer cells exemplified by the MDA-MB-231 and MDA-MB-436 cell lines …

Many types of cancer cells require a supply of fatty acids (FA) for growth and survival, and
interrupting de novo FA synthesis in model systems causes potent anticancer effects. We …

One of the most important metabolic hallmarks of cancer cells is enhanced lipogenesis.
Depending on the tumor type, tumor cells synthesize up to 95% of saturated and mono …

Cells obtain FAs either from LPL-catalyzed hydrolysis of lipoprotein triglyceride or from
unesterified FFAs associated with albumin. LPL also influences uptake of esterified lipids …

Abstract Purpose: Omega-3 (n-3) fatty acids (FA) have been proposed to confer tumor-
inhibitory properties. In vivo, dietary FA are delivered to tumor cells by two main routes: low …

Mice fed menhaden (fish) oil or coconut oil‐rich diets were inoculated intraperitoneally with
a rapidly growing leukemia, T27A. After one week, the tumor cells were harvested, and51Cr …

In order to exert metabolic effects, fatty acids must be taken up by cells and metabolize
effectively to different classes of cellular lipids (triacylglycerols, phospholipids, etc.) for …

Malignant tumors increase the levels of triacylglycerol carriers, ie, very low density
lipoproteins (VLDL), and lower the concentrations of cholesterol carriers, ie, low-density and …

Background The highest incidence of breast cancer is in the Western world. Several aspects
of the Western lifestyle are known risk factors for breast cancer. In particular, previous …