Neurodevelopmental and neuropsychiatric disorders (such as autism spectrum disorder)
have broad health implications for children, with no definitive cure for the vast majority of …

The isolation and identification, in 1964, of delta-9-tetrahydrocannabinol (THC), the primary
psychoactive compound in cannabis, opened the door to a whole new field of medical …

Cannabis-derived compounds, such as cannabidiol (CBD) and delta-9-trans-
tetrahydrocannabinol (THC), are increasingly prescribed for a range of clinical indications …

During the last decades, researchers have investigated the functional relevance of adult
hippocampal neurogenesis in normal brain function as well as in the pathogenesis of …

The endocannabinoid retrograde signaling pathway is widely expressed in the central
nervous system, where it plays major roles in regulating synaptic plasticity (excitatory and …

A better understanding of the endocannabinoid system and a relaxation in regulatory control
of cannabis globally has increased interest in the medicinal use of cannabinoid-based …

Rationale Autism spectrum disorder (ASD) is defined as a group of neurodevelopmental
disorders whose symptoms include impaired communication and social interaction …

Abstract Autism Spectrum Disorder (ASD) is characterized by persistent deficits in social
communication, restricted and repetitive patterns of behavior, interests, or activities and often …

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorderaffecting
over 1% of the general population. While it is well established that ASD stems from a …

2 Global Pediatric Health autism spectrum disorder. Despite the broadening of the search
criteria, no clinical trials were found using these terms. The search did reveal one ongoing …