Introduction The association between a change in proteinuria over time and its impact on
kidney prognosis has not been analysed in complement component 3 (C3) glomerulopathy …

Results Eighty patients with C3 glomerulopathy were identified: 21 with DDD and 59 with
C3GN. Patients with DDD were younger, more likely to have low serum C3 levels, and more …

C3 glomerulopathy (C3G) is a rare complement-mediated disease. Specific treatments are
not yet available and factors predictive of kidney survival such as age, kidney function and …

Rationale & Objective A previous study that evaluated associations of kidney biopsy findings
with disease progression in patients with C3 glomerulopathy (C3G) proposed a prognostic …

Abstract 'C3 glomerulopathy'is a recent disease classification comprising several rare types
of glomerulonephritis (GN), including dense deposit disease (DDD), C3 glomerulonephritis …

Background: C3 glomerulopathy (C3G), a rare glomerular disease mediated by alternative
complement pathway dysregulation, is associated with a high rate of recurrence and graft …

Abstract Background: C3 glomerulopathy (C3GP) is a recently identified and described
disease that has a high risk of progressing into end-stage renal disease. We aimed to …

C3 glomerulopathy refers to a disease process in which abnormal control of complement
activation, degradation or deposition results in predominant C3 fragment deposition within …

Results Assessment of the alternative complement pathway showed that compared with
controls, patients with C3G had lower levels of serum C3 (P< 0.001 for both DDD and …

Abstract C3 glomerulopathy (C3G) is a clinicopathologic entity secondary to dysregulation of
the alternative complement pathway in plasma and the glomerular microenvironment. The …