The wingless/int1 (WNT)/F rizzled (FZD) signalling pathway controls numerous cellular
processes such as proliferation, differentiation, cell‐fate decisions, migration and plays a …

For more than 30 years, WNT/β-catenin and planar cell polarity signaling has formed the
basis for what we understand to be the primary output of the interaction between WNTs and …

The seven-transmembrane-spanning receptors of the FZD 1–10 class are bound and
activated by the WNT family of lipoglycoproteins, thereby inducing a complex network of …

The Frizzled (FZD) family of receptors is critically involved in embryogenesis, and there is
substantial evidence that members of this family also regulate tissue homeostasis in many …

The lipoglycoproteins of the mammalian WNT family induce β-catenin-dependent signaling
through interaction with members of the Class Frizzled receptors and LDL receptor-related …

Frizzleds (FZDs) are a group of seven transmembrane–spanning (7TM) receptors that
belong to class F of the G protein–coupled receptor (GPCR) superfamily. FZDs bind WNT …

The Wingless/Int1 (Wnt) signaling system plays multiple, essential roles in embryonic
development, tissue homeostasis, and human diseases. Although many of the underlying …

Wingless/integrase-1 (WNT) signaling is a key pathway regulating various aspects of
embryonic development; however it also underlies several pathological conditions in man …

Receptors of the Fz (Frizzled) family initiate Wnt ligand-dependent signalling controlling
multiple steps in organism development and carcinogenesis. Fz proteins possess seven …

The WNT receptors of the Frizzled family comprise ten mammalian isoforms, bind WNT
proteins and mediate downstream signaling to regulate stem cell fate, neuronal …