ABSTRACT A vast array of successive epigenetic modifications ensures the creation of a
healthy individual. Crucial epigenetic reprogramming events occur during germ cell …

Although assisted reproductive technology (ART) has become a routine practice for human
infertility treatment, the etiology of the increased risks for perinatal problems in ART …

ABSTRACT Children conceived by Assisted Reproductive Technologies (ART) are at
moderately increased risk for a number of undesirable outcomes, including low birth weight …

A considerable proportion of offspring, in particular in ruminants and mice, born from nuclear
transfer (NT)-derived and in-vitro-produced (IVP) embryos is affected by multiple …

Developmental pathways in humans and other organisms are buffered against changes in
genotype and environment. Therefore, it should not come as a surprise that most of the …

The advent of in vitro fertilization (IVF) in animals and humans implies an extraordinary
change in the environment where the beginning of a new organism takes place. In mammals …

Live birthrates following assisted reproduction account for 1 to 3% of pregnancies in
developed countries, and these figures seem set to rise. Concerns regarding the safe use of …

The foetal origins of adult diseases or Barker hypothesis suggests that there can be adverse
in uterus effects on the foetus that can lead to certain diseases in adults. Extending this …

There is concern about the health of children who are conceived with the use assisted
reproductive technologies (ART). In addition to reports of low birth weight and chromosomal …

A broad spectrum of assisted reproductive technologies has become available for couples
with fertility problems. Follow-up studies of children born as a result of assisted reproduction …