Studies have shown that miR-221 and miR-222 are deregulated in many cancers, including
prostate cancer. Nevertheless, the biological role and the underlying mechanisms of miR …

The purpose of this study was to elucidate the molecular mechanisms of microRNA-205
(miR-205) as a tumor suppressor in prostate cancer (PCa). In the present study, microRNA …

MicroRNAs have been implicated in regulating diverse cellular pathways. Emerging
evidence indicates that miR-143 plays causal roles in cancer tumorigenesis as a tumor …

Abstract Introduction Prostate cancer (PCa) is one of the most common types of cancer in
men. In the course of the development and progression of this disease, abnormal …

Background The downregulation of the tumor suppressor miR200c plays important roles in
many malignant tumors. This study aims to show that miR200c is a posttranscriptional …

Background To investigate the effect of miR-221-5p on cell proliferaton and metastasis of
human prostate cancer in vitro and vivo. Methods We established PC3 cell lines with stable …

MicroRNA-34a (miR-34a) functions as a tumor suppressor gene and inhibits abnormal cell
growth by regulating the expression of other genes. The role of miR-34a in regulating sirtuin …

Abstract hsa-miR-195-5p (miR-195) has been proven to be a critical regulator in the
progression of prostate cancer (PCa). To identify additional targets and molecular functions …

Castration‐resistant prostate cancer (CRPC) and its treatment are challenging issues in
prostate cancer management. Here, we report that miR‐663 is upregulated in CRPC tissues …

Background Castrate‐resistant prostate cancer (CRPC) is an aggressive and lethal disease.
The pathogenesis of CRPC is not fully understood and novel therapeutic targets need to be …