The role of intestinal microbiota in the development and severity of chemotherapy-induced mucositis

MJ Van Vliet, HJM Harmsen, ESJM de Bont… - PLoS …, 2010 - journals.plos.org
Mucositis, also referred to as mucosal barrier injury, is one of the most debilitating side
effects of radiotherapy and chemotherapy treatment. Clinically, mucositis is associated with …

Chemotherapy-induced intestinal microbiota dysbiosis impairs mucosal homeostasis by modulating toll-like receptor signaling pathways

L Wei, XS Wen, CJ Xian - International journal of molecular sciences, 2021 - mdpi.com
Chemotherapy-induced intestinal mucositis, a painful debilitating condition affecting up to 40–
100% of patients undergoing chemotherapy, can reduce the patients' quality of life, add …

Interaction between host cells and microbes in chemotherapy-induced mucositis

AM Stringer - Nutrients, 2013 - mdpi.com
Cancer patients receiving chemotherapy often develop mucositis as a direct result of their
treatment. Recently, the intestinal microbiota has attracted significant attention in the …

Systematic review: the role of the gut microbiota in chemotherapy‐or radiation‐induced gastrointestinal mucositis–current evidence and potential clinical applications

Y Touchefeu, E Montassier, K Nieman… - Alimentary …, 2014 - Wiley Online Library
Background Gastrointestinal mucositis is defined as inflammation and/or ulcers of the
gastrointestinal tract occurring as a complication of chemotherapy and radiation therapy …

Substantial decreases in the number and diversity of microbiota during chemotherapy-induced gastrointestinal mucositis in a rat model

M Fijlstra, M Ferdous, AM Koning, EHHM Rings… - Supportive care in …, 2015 - Springer
Purpose Earlier, we showed in acute myeloid leukemia (AML) patients that the microbiota
changes dramatically during anticancer treatment, coinciding with gastrointestinal mucositis …

Gut microbiota: implications for radiotherapy response and radiotherapy-induced mucositis

G Al-Qadami, Y Van Sebille, H Le… - Expert review of …, 2019 - Taylor & Francis
Introduction: Radiotherapy is a mainstay of solid tumor management but can be associated
with unacceptable levels of off-target tissue toxicity which impact treatment outcomes and …

[HTML][HTML] Host/microbiota interactions in health and diseases—Time for mucosal microbiology!

N Daniel, E Lécuyer, B Chassaing - Mucosal Immunology, 2021 - Elsevier
During the last 20 years, a new field of research delineating the importance of the microbiota
in health and diseases has emerged. Inappropriate host-microbiota interactions have been …

[HTML][HTML] Understanding chemotherapy-induced intestinal mucositis and strategies to improve gut resilience

AT Sougiannis, BN VanderVeen… - American Journal …, 2021 - journals.physiology.org
Intestinal mucositis remains one of the most debilitating side effects related to
chemotherapy. The onset and persistence of mucositis is an intricate physiological process …

Microbiota dysbiosis and barrier dysfunction in inflammatory bowel disease and colorectal cancers: exploring a common ground hypothesis

LCH Yu - Journal of biomedical science, 2018 - Springer
Inflammatory bowel disease (IBD) is a multifactorial disease which arises as a result of the
interaction of genetic, environmental, barrier and microbial factors leading to chronic …

Interactions of commensal and pathogenic microorganisms with the mucus layer in the colon

R Cai, C Cheng, J Chen, X Xu, C Ding, B Gu - Gut microbes, 2020 - Taylor & Francis
The intestinal mucosal barrier, which is composed of epithelial cells and mucus layers
secreted by goblet cells and contains commensal bacteria, constitutes the first line of …