Chagas cardiomyopathy is the most frequent and most severe manifestation of chronic
Chagas disease, and is one of the leading causes of morbidity and death in Latin America …

Among the pathophysiological derangements operating in the chronic phase of Chagas
disease, parasite persistence is likely to constitute the main mechanism of myocardial injury …

Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, infects nearly 18
million people in Latin America and mainly affects the heart, causing heart failure …

BACKGROUND: Benznidazole is effective for treating acute and chronic (recently acquired)
Trypanosoma cruzi infection (Chagas' disease). Recent data indicate that parasite …

Chagas disease (CD) is a tropical vector-borne infection caused by the protozoan parasite
Trypanosoma cruzi (T. cruzi), also known as American Trypanosomiasis. It is considered …

Chagas heart disease (CHD) results from infection with the protozoan parasite
Trypanosoma cruzi and is the leading cause of infectious myocarditis worldwide. It poses a …

Background The role of trypanocidal therapy in patients with established Chagas'
cardiomyopathy is unproven. Methods We conducted a prospective, multicenter …

Chagas cardiomyopathy is the most severe and life-threatening manifestation of human
Chagas disease—a'neglected'tropical disease caused by the protozoan parasite …

Chagas' disease, caused by Trypanosoma cruzi infection, is ranked as the most serious
parasitic disease in Latin America. Nearly 30% of infected patients develop life-threatening …

The pathogenesis and evolutive pattern of Chagas disease suggests that the chronic phase
should be more widely treated in order to (i) eliminate Trypanosoma cruzi and prevent new …