Introduction Serum hyaluronic acid (sHA) is a serum biomarker for knee osteoarthritis (OA).
Although sHA concentration is elevated in patients with knee OA, the relationship between …

Objective We investigated the relationship between the molecular weight (MW) distribution
of hyaluronan (HA) in synovial fluid (SF) and risk of knee osteoarthritis (OA) progression …

Backgroud While serum levels of hyarulonic acid (sHA) is known to be useful for a burden of
disease biomarker in knee OA, it is far from practical. The reference intervals must be …

Objective. To investigate the prognostic value of serum hyaluronic acid (HA) and keratan
sulfate (KS) levels in relation to tibiofemoral osteoarthritis (OA) of the knee. Methods. Clinical …

Objective Serum hyaluronan (HA) has been proposed as a potential biomarker of
osteoarthritis (OA). We examined associations between serum HA and radiographic OA in …

OBJECTIVE: To investigate relationship between serum hyaluronan (HA) level and the
presence and severity of radiographic knee osteoarthritis (OA) as well as degree of knee …

Purpose Although serum hyaluronan (HA) levels increase in patients with osteoarthritis
(OA), the association between OA severity and elevation of serum HA levels is not clear. Our …

Background One potential mechanism for early superficial cartilage wear in normal joints is
alteration of the lubricant content and quality of synovial fluid. The purpose of this study was …

Study objectives: To study prognostic value of different biochemical markers for
morphological progression of early knee osteoarthritis. Design: A total of 89 patients with …

OBJECTIVE: Intraarticular (IA) hylan injections constitute second-line therapy for
osteoarthritis (OA) of the knee, but human studies suggesting a possible mechanism of …