Understanding the post‐translational modifications of targeted proteins is of great
significance for manipulating the physiological processes of eukaryotes. Chemical biology …

Proteins are the workhorses of the cell, playing crucial roles in virtually every biological
process. The revolutionary ability to visualize and monitor proteins in living systems, which is …

Modifications by kinases are a fast and reversible mechanism to diversify the function of the
targeted proteins. The OCT4 transcription factor is essential for preimplantation development …

Proteins are intriguing biomacromolecules for all living systems, not only as essential
building blocks of organisms, but also as participants in almost every aspect of cellular …

Various post-translational modifications can naturally occur on proteins, regulating the
activity, subcellular localization, interaction, or stability of the proteins. However, it can be …

Protein posttranslational modifications (PTMs) play critical roles in regulating cellular
activities. Here we provide a survey of genetic code expansion (GCE) methods that were …

Posttranslational modification (PTM) is a key mechanism for regulating diverse protein
functions, and thus critically affects many essential biological processes. Critical for …

Post-translational modifications (PTMs) play important roles in regulating a variety of
biological processes. To facilitate PTM studies, the genetic code expansion strategy has …

A large array of posttranslational modifications can dramatically change the properties of
proteins and influence different aspects of their biological function such as enzymatic …

Proteins are key biomolecules for most biological processes, their function is related to their
conformation that is also dictated by their sequence of amino acids. Through evolution …