Impaired wound healing is one of the severe complications of diabetes. Macrophages have
been shown to play a vital role in wound healing. In different wound environments …

Diabetes mellitus is a costly disease and nearly one-third of these costs are attributed to
management of diabetic foot disease including chronic, non-healing, diabetic foot ulcers …

Diabetes is a chronic metabolic disorder that poses a global burden to healthcare.
Increasing incidence of diabetes-related complications in the affected population includes a …

A major challenge in the field of diabetic wound healing is to confirm the body's intrinsic
mechanism that could sense the immune system damage promptly and protect the wound …

Macrophages play a prominent role in wound healing. In the early stages, they promote
inflammation and remove pathogens, wound debris, and cells that have apoptosed. Later in …

Non-healing wounds in Type 2 Diabetes (T2D) patients represent the most common cause
of amputation in the US, with an associated 5-year mortality of nearly 50%. Our lab has …

Macrophages play a critical role in wound healing and can be activated to two distinctive
phenotypes in vitro: classical macrophage activation (caM) and alternative macrophage …

Wound healing of postnatal mammalian dermal tissue is a complex multistep process, which
at best restores barrier function of the skin and results in scar formation in normal patients …

Macrophage differentiation and polarization are essential players in the success of the
wound-healing process. Acute simple wounds progress from inflammation to proliferation …

Background Impaired wound healing is the most common and significant complication of
Diabetes. While most other complications of Diabetes have better treatment options, diabetic …