AKT is implicated in neurological disorders. AKT has three isoforms, AKT1/AKT2/AKT3, with
brain cell type-specific expression that may differentially influence behavior. Therefore, we …

The serine/threonine protein kinase v-AKT homologs (AKTs), are implicated in typical and
atypical neurodevelopment. Akt isoforms Akt1, Akt2, and Akt3 have been extensively studied …

The protein kinase B (PKB/Akt), found in three distinctive isoforms (PKBα/Akt1, PKBβ/Akt2,
PKBγ/Akt3), is implicated in a variety of cellular processes such as cell development, growth …

Psychiatric genetic studies have identified genome-wide significant loci for schizophrenia.
The AKT3/1q44 locus is a principal risk region and gene-network analyses identify AKT3 …

There is accumulating evidence that AKT signaling plays a role in the pathogenesis of
schizophrenia. We asked whether Akt1 deficiency in mice results in structural and functional …

AKT1 controls important processes in medial temporal lobe (MTL) development and
plasticity, but the impact of human genetic variation in AKT1 on these processes is not …

Background: The economic burden associated with major depressive disorder and anxiety
disorders render both disorders the most common and debilitating psychiatric illnesses. To …

Aim Loss‐of‐function mutation of Akt3 in humans has been associated with microcephaly
and cognitive defects. Two Akt isoforms, Akt1 and Akt3, are highly expressed in …

Genetic studies have associated deficient function of the serine/threonine kinase Akt1 with
schizophrenia. This disorder is associated with developmental, structural, and functional …

AKT is a kinase regulating numerous cellular processes in the brain, and mutations in AKT
are known to affect brain function. AKT is indirectly implicated in synaptic plasticity, but its …