Curcumin reduces inflammation in knee osteoarthritis rats through blocking TLR4/MyD88/NF‐κB signal pathway
Y Zhang, Y Zeng - Drug Development Research, 2019 - Wiley Online Library
Abstract Preclinical Research & Development Curcumin has been shown to possess a
series of beneficial effects, such as antiinflammatory, antioxidant, analgesic, and promoting …
series of beneficial effects, such as antiinflammatory, antioxidant, analgesic, and promoting …
A Next Generation Formulation of Curcumin Ameliorates Experimentally Induced Osteoarthritis in Rats via Regulation of Inflammatory Mediators
Osteoarthritis (OA) is a chronic and debilitating disease of the knee joint. OA of the knee is
initiated by physical damage and accumulated oxidative stress, followed by an exaggerated …
initiated by physical damage and accumulated oxidative stress, followed by an exaggerated …
Combined Administration of Curcumin and Chondroitin Sulfate Alleviates Cartilage Injury and Inflammation via NF-κB Pathway in Knee Osteoarthritis Rats
T Guan, LG Ding, BY Lu, JY Guo, MY Wu… - Frontiers in …, 2022 - frontiersin.org
Objective: Osteoarthritis (OA) is a degenerative chronic disease that most often occurs in the
knee joint. Studies have shown that some food supplements, such as curcumin and …
knee joint. Studies have shown that some food supplements, such as curcumin and …
Curcumin attenuates collagen-induced rat arthritis via anti-inflammatory and apoptotic effects
Q Wang, C Ye, S Sun, R Li, X Shi, S Wang… - International …, 2019 - Elsevier
Curcumin is a natural herbal product that has been popularly used to treat autoimmune
diseases in China; however, its effects on rheumatoid arthritis and its mechanism are not …
diseases in China; however, its effects on rheumatoid arthritis and its mechanism are not …
Curcumin attenuates inflammatory response in IL-1β-induced human synovial fibroblasts and collagen-induced arthritis in mouse model
DO Moon, MO Kim, YH Choi, YM Park… - International …, 2010 - Elsevier
Curcumin, a major component of turmeric, has been shown to exhibit anti-oxidant and anti-
inflammatory activities. The present study was performed to determine whether curcumin is …
inflammatory activities. The present study was performed to determine whether curcumin is …
The spice for joint inflammation: anti-inflammatory role of curcumin in treating osteoarthritis
KY Chin - Drug design, development and therapy, 2016 - Taylor & Francis
Osteoarthritis is a degenerative disease of the joint affecting aging populations worldwide. It
has an underlying inflammatory cause, which contributes to the loss of chondrocytes …
has an underlying inflammatory cause, which contributes to the loss of chondrocytes …
Curcumin alleviates rheumatoid arthritis-induced inflammation and synovial hyperplasia by targeting mTOR pathway in rats
Q Dai, D Zhou, L Xu, X Song - Drug design, development and …, 2018 - Taylor & Francis
Purpose Rheumatoid arthritis (RA) is a chronic, progressive autoimmune disease
characterized by aggressive and symmetric polyarthritis. Mammalian target of rapamycin …
characterized by aggressive and symmetric polyarthritis. Mammalian target of rapamycin …
Curcumin prevents osteoarthritis by inhibiting the activation of inflammasome NLRP3
Y Sun, W Liu, H Zhang, H Li, J Liu, F Zhang… - Journal of Interferon & …, 2017 - liebertpub.com
Curcumin has shown protective potential on osteoarthritis. However, its effect on treatment of
osteoarthritis remains elusive so far. This study aimed to determine whether curcumin could …
osteoarthritis remains elusive so far. This study aimed to determine whether curcumin could …
Evaluation of the articular cartilage in the knees of rats with induced arthritis treated with curcumin
This study was designed to evaluate the anti-inflammatory effects of a curcumin treatment on
the knee of rats with induced osteoarthritis. Fifteen adult rats were used and divided in three …
the knee of rats with induced osteoarthritis. Fifteen adult rats were used and divided in three …
Regulation of type II collagen, matrix metalloproteinase-13 and cell proliferation by interleukin-1β is mediated by curcumin via inhibition of NF-κB signaling in rat …
J Wang, J Ma, JH Gu, FY Wang… - Molecular …, 2017 - spandidos-publications.com
Curcumin possesses strong anti-inflammatory, anti-rheumatoid and anti-oxidative activities,
and has the potential to inhibit nuclear factor-κB (NF-κB) signaling. Cartilage damage in …
and has the potential to inhibit nuclear factor-κB (NF-κB) signaling. Cartilage damage in …