Live enteroviruses, but not other viruses, detected in human pancreas at the onset of type 1 diabetes in the DiViD study
L Krogvold, A Genoni, A Puggioni, D Campani… - Diabetologia, 2022 - Springer
Aims/hypothesis Enterovirus (EV) infection of pancreatic islet cells is one possible factor
contributing to type 1 diabetes development. We have reported the presence of EV genome …
contributing to type 1 diabetes development. We have reported the presence of EV genome …
Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study
S Oikarinen, L Krogvold, B Edwin, T Buanes… - Diabetologia, 2021 - Springer
Abstract Aims/hypothesis The Diabetes Virus Detection (DiViD) study is the first study to
laparoscopically collect pancreatic tissue and purified pancreatic islets together with …
laparoscopically collect pancreatic tissue and purified pancreatic islets together with …
Effects on isolated human pancreatic islet cells after infection with strains of enterovirus isolated at clinical presentation of type 1 diabetes
A Elshebani, A Olsson, J Westman, T Tuvemo… - Virus research, 2007 - Elsevier
Enterovirus (EV) infections have been associated with the pathogenesis of type 1 diabetes
(T1D). They may cause β-cell destruction either by cytolytic infection of the cells or indirectly …
(T1D). They may cause β-cell destruction either by cytolytic infection of the cells or indirectly …
Evaluation of RT-PCR and immunohistochemistry as tools for detection of enterovirus in the human pancreas and islets of Langerhans
O Skog, S Ingvast, O Korsgren - Journal of Clinical Virology, 2014 - Elsevier
Background Enteroviruses have been implicated in the etiology of type 1 diabetes,
supported by immunoreactivity of enteroviral protein in islets, but presence of enteroviral …
supported by immunoreactivity of enteroviral protein in islets, but presence of enteroviral …
Role of enteroviruses in the pathogenesis of type 1 diabetes
M Roivainen, K Klingel - Diabetologia, 2009 - Springer
The pathogenesis of type 1 diabetes is widely believed to involve T cell-mediated
autoimmune processes directed against the insulin-producing beta cells in the pancreas …
autoimmune processes directed against the insulin-producing beta cells in the pancreas …
Enteroviruses and type 1 diabetes
S Tracy, KM Drescher… - … Metabolism Research and …, 2011 - Wiley Online Library
Background Human enteroviruses, which are transmitted via a faecal‐oral route, have long
been associated with type 1 diabetes onset. Increased hygiene in the 20th century may now …
been associated with type 1 diabetes onset. Increased hygiene in the 20th century may now …
Detection of a low-grade enteroviral infection in the islets of langerhans of living patients newly diagnosed with type 1 diabetes
The Diabetes Virus Detection study (DiViD) is the first to examine fresh pancreatic tissue at
the diagnosis of type 1 diabetes for the presence of viruses. Minimal pancreatic tail resection …
the diagnosis of type 1 diabetes for the presence of viruses. Minimal pancreatic tail resection …
Enteroviral infections as a trigger for type 1 diabetes
T Rodriguez-Calvo - Current diabetes reports, 2018 - Springer
Abstract Purpose of Review To provide an overview of studies that have detected
enteroviruses (EV) in samples from people with type 1 diabetes (T1D), the techniques they …
enteroviruses (EV) in samples from people with type 1 diabetes (T1D), the techniques they …
Recent enterovirus infection in type 1 diabetes: evidence with a novel IgM method
A Elfaitouri, AK Berg, G Frisk, H Yin… - Journal of medical …, 2007 - Wiley Online Library
Enterovirus (EV) infection has been associated with Type 1 (T1D) diabetes and on a few
occasions virus could be isolated at onset of the disease. Using two such isolates as …
occasions virus could be isolated at onset of the disease. Using two such isolates as …
Enteroviruses: new findings on the role of enteroviruses in type 1 diabetes
M Roivainen - The international journal of biochemistry & cell biology, 2006 - Elsevier
Common enterovirus infections appear to initiate or facilitate the pathogenetic processes
leading to type 1 diabetes, and sometimes also precipitate the clinical disease. It is not …
leading to type 1 diabetes, and sometimes also precipitate the clinical disease. It is not …