Drug repurposing for viral infectious diseases: how far are we?
B Mercorelli, G Palù, A Loregian - Trends in microbiology, 2018 - cell.com
Despite the recent advances in controlling some viral pathogens, most viral infections still
lack specific treatment. Indeed, the need for effective therapeutic strategies to combat 'old' …
lack specific treatment. Indeed, the need for effective therapeutic strategies to combat 'old' …
Drug repurposing for new, efficient, broad spectrum antivirals
M García-Serradilla, C Risco, B Pacheco - Virus research, 2019 - Elsevier
Emerging viruses are a major threat to human health. Recent outbreaks have emphasized
the urgent need for new antiviral treatments. For several pathogenic viruses, considerable …
the urgent need for new antiviral treatments. For several pathogenic viruses, considerable …
Drug repurposing: a better approach for infectious disease drug discovery?
GL Law, J Tisoncik-Go, MJ Korth, MG Katze - Current opinion in …, 2013 - Elsevier
Highlights•Infectious disease investigators need to embrace new drug repurposing
approaches.•Key components include public databases and predictive computational …
approaches.•Key components include public databases and predictive computational …
Target repurposing for neglected diseases
MP Pollastri, RK Campbell - Future medicinal chemistry, 2011 - Taylor & Francis
Infectious diseases are an enormous burden to global health and, since drug discovery is
costly, those infectious diseases that affect the developing world are often not pursued by …
costly, those infectious diseases that affect the developing world are often not pursued by …
Drug repurposing screens and synergistic drug‐combinations for infectious diseases
Infectious diseases account for nearly one fifth of the worldwide death toll every year. The
continuous increase of drug‐resistant pathogens is a big challenge for treatment of …
continuous increase of drug‐resistant pathogens is a big challenge for treatment of …
Drug repurposing for antimicrobial discovery
Antimicrobial resistance continues to be a public threat on a global scale. The ongoing need
to develop new antimicrobial drugs that are effective against multi-drug-resistant pathogens …
to develop new antimicrobial drugs that are effective against multi-drug-resistant pathogens …
Drug repurposing for the treatment of bacterial and fungal infections
A Miró-Canturri, R Ayerbe-Algaba… - Frontiers in microbiology, 2019 - frontiersin.org
Multidrug-resistant (MDR) pathogens pose a well-recognized global health threat that
demands effective solutions; the situation is deemed a global priority by the World Health …
demands effective solutions; the situation is deemed a global priority by the World Health …
Drug repurposing to overcome microbial resistance
J Jampilek - Drug Discovery Today, 2022 - Elsevier
Infections are a growing global threat, and the number of resistant species of microbial
pathogens is alarming. However, the rapid development of cross-resistant or multidrug …
pathogens is alarming. However, the rapid development of cross-resistant or multidrug …
Recent drug-repurposing-driven advances in the discovery of novel antibiotics
Drug repurposing is a safe and successful pathway to speed up the novel drug discovery
and development processes compared with de novo drug discovery approaches. Drug …
and development processes compared with de novo drug discovery approaches. Drug …
Drug repurposing as an alternative for the treatment of recalcitrant bacterial infections
A Rangel-Vega, LR Bernstein… - Frontiers in …, 2015 - frontiersin.org
Bacterial infection remains one of the leading causes of death worldwide, and the options for
treating such infections are decreasing, due the rise of antibiotic-resistant bacteria. The …
treating such infections are decreasing, due the rise of antibiotic-resistant bacteria. The …