Aquaporin 0 (AQP0), essential for lens clarity, is a tetrameric protein composed of four
identical monomers, each of which has its own water pore. The water permeability of AQP0 …

Purpose.: The zebrafish lens is well suited for studies of physiology and development due to
its rapid formation in the embryo and genetic accessibility. Aquaporin 0 (AQP0), a lens …

We previously showed that the water permeability of AQP0, the water channel of the lens,
increases with acid pH and that His40 is required (Németh-Cahalan, KL, and JE Hall. 2000 …

purpose. To examine Ca 2+-and pH-mediated regulation of water permeability of
endogenously expressed aquaporin (AQP) 0 in lens fiber cells and AQP1 in lens epithelial …

Compared to other aquaporins (AQPs), lens-specific AQP0 is a poor water channel, and its
permeability was reported to be pH-dependent. To date, most water conduction studies on …

Aquaporin-0 (AQP0) is the main water channel in the mammalian lens and is involved in
accommodation and maintaining lens transparency. AQP0 binds the Ca2+-sensing protein …

ABSTRACT Purpose: Although aquaporin 0 (AQP0) is a member of the AQP family, it has
limited water permeability compared with other members. AQP0 may also have cell …

Aquaporin 0 (AQP0) is the major intrinsic protein of the lens and its water permeability can
be modulated by changes in pH and Ca2+. The Cataract Fraser (CatFr) mouse accumulates …

Purpose To study the interaction between the lens-specific water channel protein, aquaporin
0 (AQP0) and the lens-specific intermediate filament protein, filensin, and the effect of this …

Abstract Aquaporin 0 (AQP0) and AQP1 are expressed in the lens, each in a different cell
type, and their functional roles are not thoroughly understood. Our previous study showed …