Promises of microbiome-based therapies

JS Bajaj, SC Ng, B Schnabl - Journal of hepatology, 2022 - Elsevier
Humans harbour large quantities of microbes, including bacteria, fungi, viruses and
archaea, in the gut. Patients with liver disease exhibit changes in the intestinal microbiota …

[HTML][HTML] The role of the gut microbiome in chronic liver disease: the clinical evidence revised

KJP Schwenger, N Clermont-Dejean, JP Allard - JHEP Reports, 2019 - Elsevier
Recent research has suggested a role for the intestinal microbiota in the pathogenesis and
potential treatment of a wide range of liver diseases. The intestinal microbiota and bacterial …

Novel approaches to intervene gut microbiota in the treatment of chronic liver diseases

C Liu, YL Wang, YY Yang, NP Zhang, C Niu… - The FASEB …, 2021 - Wiley Online Library
Recent investigations of gut microbiota have contributed to understanding of the critical role
of microbial community in pathophysiology. Dysbiosis not only causes disturbance directly to …

Intestinal microbiota in liver disease

TR Haque, AS Barritt IV - Best Practice & Research Clinical …, 2016 - Elsevier
The intestinal microbiota have emerged as a topic of intense interest in gastroenterology
and hepatology. The liver is on the front line as the first filter of nutrients, toxins and bacterial …

the gut microbiome as a therapeutic target in the pathogenesis and treatment of chronic liver disease

CA Woodhouse, VC Patel… - Alimentary …, 2018 - Wiley Online Library
Background Mortality from chronic liver disease is rising exponentially. The liver is intimately
linked to the gut via the portal vein, and exposure to gut microbiota and their metabolites …

The gut–liver axis and the intersection with the microbiome

A Tripathi, J Debelius, DA Brenner, M Karin… - Nature reviews …, 2018 - nature.com
In the past decade, an exciting realization has been that diverse liver diseases—ranging
from nonalcoholic steatohepatitis, alcoholic steatohepatitis and cirrhosis to hepatocellular …

[HTML][HTML] Modulating the intestinal microbiota: therapeutic opportunities in liver disease

CA Philips, P Augustine, PK Yerol… - Journal of clinical and …, 2020 - ncbi.nlm.nih.gov
Gut microbiota has been demonstrated to have a significant impact on the initiation,
progression and development of complications associated with multiple liver diseases …

The gut–liver axis and gut microbiota in health and liver disease

CL Hsu, B Schnabl - Nature Reviews Microbiology, 2023 - nature.com
The trillions of microorganisms in the human intestine are important regulators of health, and
disruptions in the gut microbial communities can cause disease. The gut, liver and immune …

Gut microbiota targeted approach in the management of chronic liver diseases

J Liu, D Yang, X Wang, PT Asare, Q Zhang… - Frontiers in cellular …, 2022 - frontiersin.org
The liver is directly connected to the intestines through the portal vein, which enables the gut
microbiota and gut-derived products to influence liver health. There is accumulating …

[HTML][HTML] Gut microbiota mediated molecular events and therapy in liver diseases

X Qi, M Yang, J Stenberg, R Dey, L Fogwe… - World Journal of …, 2020 - ncbi.nlm.nih.gov
Gut microbiota is a community of microorganisms that reside in the gastrointestinal tract. An
increasing number of studies has demonstrated that the gut-liver axis plays a critical role in …