Cisplatin is an effective chemotherapy drug widely used in the treatment of various solid
tumors. However, the clinical usage of cisplatin is limited by its nephrotoxicity. Isorhamnetin …

Objective Isorhamnetin (IH) has been reported to have significant anti-inflammatory effects in
various diseases, but its role and mechanism in AKI remain unclear. This study aimed to …

Acute kidney injury (AKI) is a common complication of hospitalization with high mortality.
Approximately 30% of patients receiving cisplatin, the first-line chemotherapy treatment …

Background Despite the efficacy of cisplatin as a chemotherapeutic agent against various
cancers, its clinical utility is limited by serious adverse reactions including nephrotoxicity …

Context: Currently, the outcomes of the use of cisplatin in cancer therapy is limited by
nephrotoxicity. Objective: This study aims to investigate the nephroprotective role of …

Cisplatin is a chemotherapeutant widely used in treating solid tumors, with the common side
effect of acute kidney injury (AKI). Developing effective useful agent for preventing or treating …

The flavonoid compound Isorhamnetin (IRMN) is known for its considerable
pharmacological properties, which include antioxidant and anti-inflammatory effects, as well …

Cisplatin is a chemotherapeutic agent widely used in the treatment of various cancers.
However, cisplatin can induce nephrotoxicity and neurotoxicity, limiting its dosage and …

Acute renal failure is a serious complication of the anticancer drug cisplatin. The potential
role of baicalein, a naturally occurring bioflavonoid on cisplatin-induced renal injury is …

Cisplatin is one of the most potent chemotherapy agents. However, its use is limited due to
its toxicity in normal tissues, including the kidney and ear. In particular, nephrotoxicity …