[HTML][HTML] Delamanid-containing regimens and multidrug-resistant tuberculosis: A systematic review and meta-analysis

MJ Nasiri, M Zangiabadian, E Arabpour, S Amini… - International Journal of …, 2022 - Elsevier
Introduction Multidrug-resistant tuberculosis (MDR-TB) is a life-threatening condition
needing long poly-chemotherapy regimens. As no systematic reviews/meta-analysis is …

Efficacy and safety of delamanid in combination with an optimised background regimen for treatment of multidrug-resistant tuberculosis: a multicentre, randomised …

F von Groote-Bidlingmaier, R Patientia… - The Lancet …, 2019 - thelancet.com
Background Delamanid is one of two recently approved drugs for the treatment of multidrug-
resistant tuberculosis. We aimed to evaluate the safety and efficacy of delamanid in the first …

Delamanid improves outcomes and reduces mortality in multidrug-resistant tuberculosis

V Skripconoka, M Danilovits, L Pehme… - European …, 2013 - Eur Respiratory Soc
Multidrug-resistant and extensively drug-resistant tuberculosis (TB) are associated with
worse treatment outcomes for patients, including higher mortality, than for drug-sensitive …

[HTML][HTML] Delamanid for multidrug-resistant pulmonary tuberculosis

MT Gler, V Skripconoka… - … England Journal of …, 2012 - Mass Medical Soc
Background Delamanid (OPC-67683), a nitro-dihydro-imidazooxazole derivative, is a new
antituberculosis medication that inhibits mycolic acid synthesis and has shown potent in vitro …

Delamanid: a review of its use in patients with multidrug-resistant tuberculosis

HA Blair, LJ Scott - Drugs, 2015 - Springer
Delamanid (Deltyba®), a nitroimidazo-oxazole derivative, is a new anti-tuberculosis (TB)
drug which exhibits potent in vitro and in vivo antitubercular activity against drug-susceptible …

Clinical outcomes among patients with drug-resistant tuberculosis receiving bedaquiline-or delamanid-containing regimens

RR Kempker, L Mikiashvili, Y Zhao… - Clinical infectious …, 2020 - academic.oup.com
Background Bedaquiline and delamanid are newly available drugs for treating multidrug-
resistant tuberculosis (MDR-TB); however, there are limited data guiding their use and no …

Delamanid for rifampicin-resistant tuberculosis: a retrospective study from South Africa

E Mohr, J Hughes, A Reuter, LT Duran… - European …, 2018 - Eur Respiratory Soc
Experience with delamanid (Dlm) is limited, particularly among HIV-positive individuals. We
describe early efficacy and safety data from a programmatic setting in South Africa. This was …

Outcomes of multidrug-resistant tuberculosis treated with bedaquiline or delamanid

H Hwang, H Kang, YS Kwon, D Jeon… - Clinical Infectious …, 2021 - academic.oup.com
Abstract Background Since 1 September 2016, bedaquiline and delamanid have been
administered for the treatment of patients with multidrug-resistant/rifampicin-resistant …

[HTML][HTML] Six-month response to delamanid treatment in MDR TB patients

C Hewison, G Ferlazzo, Z Avaliani… - Emerging infectious …, 2017 - ncbi.nlm.nih.gov
Delamanid, recently available for the treatment of multidrug-resistant tuberculosis (MDR TB),
has had limited use outside clinical trials. We present the early treatment results for 53 …

Safety and effectiveness outcomes from a 14-country cohort of patients with multi-drug resistant tuberculosis treated concomitantly with bedaquiline, delamanid, and …

H Huerga, U Khan, M Bastard… - Clinical Infectious …, 2022 - academic.oup.com
Background Concomitant use of bedaquiline (Bdq) and delamanid (Dlm) for multi-
drug/rifampicin resistant tuberculosis (MDR/RR-TB) has raised concerns about a potentially …